Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.62 |
| ▸ | PGR | P06401 | 4/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611503 | 0.93 | AR (0.71) | ARPGRPDE3BPDE3AGLA | |
| SCHEMBL5047714 | 0.79 | AR (0.60) | ARPGR | |
| SCHEMBL4609829 | 0.75 | AR (0.69) | ARPGR | |
| SCHEMBL4599378 | 0.74 | AR (0.68) | ARPGR | |
| SCHEMBL204299 | 0.72 | GAA (0.61) | ARPDE3BPDE3AGLAPOLB | |
| Hydrochloric Acid SCHEMBL618359 | 0.71 | GAA (0.59) | ARPDE3BPDE3AGLAPOLB | |
| SCHEMBL5134214 | 0.71 | PGR (0.80) | ARPGRPDE3BPDE3A | |
| SCHEMBL4611754 | 0.69 | PGR (1.00) | ARPGRPDE3BPDE3A | |
| SCHEMBL4611343 | 0.68 | PGR (0.75) | ARPGRPDE3BPDE3A | |
| Water SCHEMBL20506731 | 0.67 | TSHR (0.95) | ARPDE3BPDE3AGLAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909785-A2 | USE OF PROGESTERONE RECEPTOR MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1910285-A1 | CYANOPYRROLE-SULFONAMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007016385-A2 | USE OF SUBSTITUTED 5-AMINO-1H-PYRROLE-2-CARBONITRILE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007016212-A1 | CYANOPYRROLE-SULFONAMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | WYETH (US) | 2007-02-08 | — | — | WO | disclosed |