SCHEMBL459875

SCHEMBL459875

OCC1C2COCC1CN(Cc1ccccc1)C2

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 2/20 0.56
DRD2 P14416 4/20 0.51
DRD3 P35462 4/20 0.51
GBA1 P04062 1/20 0.51
GRIN2B Q13224 2/20 0.46
S1PR1 P21453 1/20 0.45
S1PR5 Q9H228 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18517577 0.88 FUCA1 (0.65) FUCA1DRD2DRD3GBA1GRIN2B
SCHEMBL742892 0.88 FUCA1 (0.65) FUCA1DRD2DRD3GBA1GRIN2B
SCHEMBL4198217 0.87 FUCA1 (0.54) FUCA1DRD2DRD3GBA1GRIN2B
Hydrochloric Acid SCHEMBL11771300 0.86 FUCA1 (0.62) FUCA1DRD2DRD3GBA1GRIN2B
SCHEMBL15996691 0.83 FUCA1 (0.69) FUCA1DRD2DRD3GBA1GRIN2B
SCHEMBL22784440 0.83 FUCA1 (0.69) FUCA1DRD2DRD3GBA1GRIN2B
SCHEMBL758420 0.83 FUCA1 (0.69) FUCA1DRD2DRD3GBA1GRIN2B
SCHEMBL22784542 0.83 FUCA1 (0.69) FUCA1DRD2DRD3GBA1GRIN2B
SCHEMBL288640 0.83 FUCA1 (0.69) FUCA1DRD2DRD3GBA1GRIN2B
SCHEMBL21724735 0.82 FUCA1 (0.57) FUCA1DRD2DRD3GBA1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011147951-A1 CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS PROSIDION LIMITED (GB) 2011-12-01 WO disclosed