Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.69 |
| ▸ | GBA1 | P04062 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | DRD3 | P35462 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22784440 | 1.00 | FUCA1 (0.69) | FUCA1GBA1DRD2DRD3ALDH1A1 | |
| SCHEMBL22784542 | 1.00 | FUCA1 (0.69) | FUCA1GBA1DRD2DRD3ALDH1A1 | |
| SCHEMBL15996691 | 1.00 | FUCA1 (0.69) | FUCA1GBA1DRD2DRD3ALDH1A1 | |
| SCHEMBL758420 | 1.00 | FUCA1 (0.69) | FUCA1GBA1DRD2DRD3ALDH1A1 | |
| SCHEMBL18517577 | 0.91 | FUCA1 (0.65) | FUCA1GBA1DRD2DRD3GRIN2B | |
| SCHEMBL742892 | 0.91 | FUCA1 (0.65) | FUCA1GBA1DRD2DRD3GRIN2B | |
| SCHEMBL23939426 | 0.89 | FUCA1 (0.68) | FUCA1GBA1DRD2DRD3ALDH1A1 | |
| SCHEMBL21561563 | 0.89 | FUCA1 (0.68) | FUCA1GBA1DRD2DRD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11771300 | 0.89 | FUCA1 (0.62) | FUCA1GBA1DRD2DRD3GRIN2B | |
| SCHEMBL1707693 | 0.86 | FUCA1 (0.68) | FUCA1GBA1DRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983401-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | Arkuda Therapeutics (US) | 2022-04-20 | — | — | EP | disclosed |
| US-10865194-B2 | Therapeutically active bicyclic-sulphonamides and pharmaceutical compositions | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2020-12-15 | — | — | US | disclosed |
| US-20190135778-A1 | THERAPEUTICALLY ACTIVE BICYCLIC-SULPHONAMIDES AND PHARMACEUTICAL COMPOSITIONS | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2019-05-09 | — | — | US | disclosed |
| EP-1932844-B1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | NIPPON SODA CO (JP) | 2015-09-02 | — | — | EP | disclosed |
| US-8912206-B2 | Pyrimidine ether derivatives and methods of use thereof | MERCK SHARP & DOHME CORP. (US) | 2014-12-16 | — | — | US | disclosed |
| US-8907095-B2 | Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 | MERCK SHARP & DOHME CORP. (US) | 2014-12-09 | — | — | US | disclosed |
| US-8822480-B2 | Bicyclic heterocycle derivatives and use thereof as GPR119 modulators | MERCK SHARP & DOHME CORP. (US) | 2014-09-02 | — | — | US | disclosed |
| US-8815876-B2 | Bicyclic heterocycle derivatives and methods of use thereof | MERCK SHARP & DOHME CORP. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8697867-B2 | Cross-linked cyclic amine compounds and agents for pest control | NIPPON SODA CO., LTD. (JP) | 2014-04-15 | — | — | US | disclosed |
| US-20130331569-A1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | NIPPON SODA CO., LTD. (JP) | 2013-12-12 | — | — | US | disclosed |
| WO-2011061679-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC. (US) | 2011-05-26 | — | — | WO | disclosed |
| WO-2011036576-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2011-03-31 | — | — | WO | disclosed |
| WO-2010128414-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010128414-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010128425-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20100285145-A1 | GPR 119 MODULATORS | PFIZER INC | 2010-11-11 | — | — | US | disclosed |
| US-20100285145-A1 | GPR 119 MODULATORS | PFIZER INC | 2010-11-11 | — | — | US | disclosed |
| US-20100285145-A1 | GPR 119 MODULATORS | PFIZER INC | 2010-11-11 | — | — | US | disclosed |
| WO-2010106457-A2 | 3-OXA-7-AZABICYCLO[3.3.1]NONANES | PFIZER INC. (US) | 2010-09-23 | — | — | WO | disclosed |
| US-20090318694-A1 | Cross-Linked Amine Compounds and Agents for Pest Control | NIPPON SODA CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135778-A1 | THERAPEUTICALLY ACTIVE BICYCLIC-SULPHONAMIDES AND PHARMACEUTICAL COMPOSITIONS | NAAA, FAAH, FAAH2 | FUCA1 458/4885GBA1 63/4885DRD2 2741/4885 |
| US-10865194-B2 | Therapeutically active bicyclic-sulphonamides and pharmaceutical compositions | NAAA, FAAH2, FAAH | FUCA1 397/4885GBA1 70/4885DRD2 1467/4885 |
| US-20100285145-A1 | GPR 119 MODULATORS | GPR119, GPR65, GPR39 | FUCA1 1888/4885GBA1 952/4885DRD2 1425/4885 |
| US-20130331569-A1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | CYCS, NPY1R, CYBB | FUCA1 4246/4885GBA1 2552/4885DRD2 731/4885 |
| US-20090318694-A1 | Cross-Linked Amine Compounds and Agents for Pest Control | CYCS, NPY1R, CYBB | FUCA1 4191/4885GBA1 2245/4885DRD2 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.