Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14142746 | 0.88 | TDP1 (0.46) | APPSNCAIDH1TDP1LMNA | |
| SCHEMBL3542220 | 0.88 | TDP1 (0.46) | APPSNCAIDH1TDP1LMNA | |
| SCHEMBL3542217 | 0.88 | TDP1 (0.46) | APPSNCAIDH1TDP1LMNA | |
| SCHEMBL3548701 | 0.86 | APP (0.36) | APPSNCAIDH1LMNAMEN1 | |
| SCHEMBL3548705 | 0.86 | APP (0.36) | APPSNCAIDH1LMNAMEN1 | |
| SCHEMBL3540811 | 0.80 | TDP1 (0.45) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL3540812 | 0.80 | TDP1 (0.45) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL3544459 | 0.80 | TDP1 (0.45) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL3544461 | 0.80 | TDP1 (0.45) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL3544458 | 0.80 | TDP1 (0.45) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161390-A1 | Ester Compound and Its Use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-07-03 | — | — | US | disclosed |
| EP-1742930-B1 | PYRETHROID PESTICIDE | SUMITOMO CHEMICAL CO (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161390-A1 | Ester Compound and Its Use | CASP3, CYP51A1, DDT | APP 1193/4885SNCA 1466/4885IDH1 3060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.