Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30462359 | 1.00 | PNMT (0.45) | PNMTCYP3A4HTR7HTR2BNPC1 | |
| SCHEMBL9228905 | 0.85 | CYP3A4 (0.43) | PNMTCYP3A4HTR7HTR2BALDH1A1 | |
| SCHEMBL7734116 | 0.83 | PNMT (0.45) | PNMTCYP3A4HTR7HTR2BNPC1 | |
| SCHEMBL11123365 | 0.82 | PNMT (0.38) | PNMTCYP3A4HTR7HTR2BNPC1 | |
| SCHEMBL8458734 | 0.80 | PNMT (0.49) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL70000 | 0.80 | PNMT (0.52) | PNMTCYP3A4HTR7HTR2BNPC1 | |
| SCHEMBL30447285 | 0.80 | PNMT (0.52) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL26982496 | 0.79 | CYP3A4 (0.44) | CYP3A4HTR7HTR2BNPC1RAB9A | |
| SCHEMBL29767423 | 0.78 | PNMT (0.50) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL28641066 | 0.78 | PNMT (0.41) | PNMTCYP3A4HTR7HTR2BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080223-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-10 | — | — | WO | disclosed |
| EP-1910279-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002639-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-04 | — | — | WO | disclosed |