Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRK2 | P25098 | 2/20 | 0.43 |
| ▸ | GRK3 | P35626 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449907 | 0.87 | MME (0.50) | FOLH1MEN1KMT2AMMENOD1 | |
| SCHEMBL4889077 | 0.87 | FOLH1 (0.54) | FOLH1MEN1KMT2AGRK2GRK3 | |
| SCHEMBL4889060 | 0.87 | FOLH1 (0.54) | FOLH1MEN1KMT2AGRK2GRK3 | |
| SCHEMBL28878543 | 0.84 | FOLH1 (0.65) | FOLH1MEN1KMT2AMTOR | |
| SCHEMBL4739485 | 0.73 | MMP2 (0.48) | MEN1KMT2AMMP2 | |
| SCHEMBL22503729 | 0.73 | FOLH1 (0.53) | FOLH1MEN1KMT2AGPR139C3AR1 | |
| SCHEMBL4599544 | 0.72 | FOLH1 (0.49) | FOLH1MMP2CA2 | |
| SCHEMBL4599538 | 0.72 | FOLH1 (0.49) | FOLH1MMP2CA2 | |
| SCHEMBL4889467 | 0.72 | MEN1 (0.46) | FOLH1MEN1KMT2AGRK2GRK3 | |
| SCHEMBL4889478 | 0.72 | MEN1 (0.46) | FOLH1MEN1KMT2AGRK2GRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910279-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002639-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-04 | — | — | WO | disclosed |