Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 17/20 | 0.69 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790986 | 0.84 | PGR (0.61) | PGRARHPGD | |
| SCHEMBL4611480 | 0.82 | PGR (1.00) | PGRAR | |
| SCHEMBL5132601 | 0.81 | PGR (0.74) | PGRARHPGDLMNA | |
| SCHEMBL4598912 | 0.79 | PGR (0.74) | PGRARHPGDLMNA | |
| SCHEMBL4660455 | 0.77 | PGR (0.49) | PGRARHPGDLMNA | |
| SCHEMBL4613209 | 0.77 | PGR (0.71) | PGRARHPGDLMNA | |
| SCHEMBL4612707 | 0.77 | PGR (0.67) | PGRARHPGDLMNA | |
| SCHEMBL4610903 | 0.76 | PGR (0.66) | PGRARHPGDLMNA | |
| SCHEMBL4611257 | 0.74 | PGR (0.63) | PGRARHPGDLMNA | |
| SCHEMBL4612011 | 0.73 | PGR (1.00) | PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909785-A2 | USE OF PROGESTERONE RECEPTOR MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1910285-A1 | CYANOPYRROLE-SULFONAMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007016385-A2 | USE OF SUBSTITUTED 5-AMINO-1H-PYRROLE-2-CARBONITRILE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007016212-A1 | CYANOPYRROLE-SULFONAMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | WYETH (US) | 2007-02-08 | — | — | WO | disclosed |