Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 20/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 20/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823310 | 1.00 | GABRG2 (0.58) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| Hydrochloric Acid SCHEMBL2823425 | 0.99 | GABRG2 (0.57) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL2828336 | 0.84 | GABRG2 (0.72) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| Hydrochloric Acid SCHEMBL2824438 | 0.84 | GABRG2 (0.60) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| Hydrochloric Acid SCHEMBL2828761 | 0.84 | GABRG2 (0.71) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| Hydrochloric Acid SCHEMBL2826643 | 0.84 | GABRG2 (0.60) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| Hydrochloric Acid SCHEMBL2828142 | 0.84 | GABRG2 (0.60) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL4599811 | 0.82 | GABRG2 (0.61) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| Hydrochloric Acid SCHEMBL2826712 | 0.81 | GABRG2 (0.60) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| Hydrochloric Acid SCHEMBL2825001 | 0.81 | GABRG2 (0.50) | GABRG2GABRB3GABRA5GABRA1GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937688-A1 | IMIDAZO BENZODIAZEPINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007042421-A1 | IMIDAZO BENZODIAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-04-19 | — | — | WO | disclosed |