Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 10/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599655 | 1.00 | SIGMAR1 (0.56) | SIGMAR1CHRM2CHRM1EBPGBA2 | |
| SCHEMBL3100817 | 1.00 | SIGMAR1 (0.56) | SIGMAR1CHRM2CHRM1EBPGBA2 | |
| SCHEMBL3106101 | 0.98 | SIGMAR1 (0.55) | SIGMAR1CHRM2CHRM1EBPGBA2 | |
| SCHEMBL6488211 | 0.98 | SIGMAR1 (0.55) | SIGMAR1CHRM2CHRM1EBPGBA2 | |
| SCHEMBL3090051 | 0.94 | SIGMAR1 (0.58) | SIGMAR1CHRM2CHRM1GBA2GAA | |
| SCHEMBL24965969 | 0.86 | SIGMAR1 (0.53) | SIGMAR1CHRM2CHRM1GAA | |
| SCHEMBL14135342 | 0.86 | SIGMAR1 (0.53) | SIGMAR1CHRM2CHRM1GAA | |
| SCHEMBL15217044 | 0.86 | SIGMAR1 (0.53) | SIGMAR1CHRM2CHRM1GAA | |
| SCHEMBL3100760 | 0.86 | SIGMAR1 (0.53) | SIGMAR1CHRM2CHRM1GAA | |
| SCHEMBL15080727 | 0.81 | SIGMAR1 (0.56) | SIGMAR1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469850-A4 | METHOD OF TREATING SEXUAL DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | ARDENT PHARMACEUTICALS INC (US) | 2008-03-12 | — | — | EP | disclosed |
| EP-1469850-A1 | METHOD OF TREATING SEXUAL DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | Ardent Pharmaceuticals, Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003057223-A1 | METHOD OF TREATING SEXUAL DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | ARDENT PHARMACEUTICALS, INC. (US) | 2003-07-17 | — | — | WO | disclosed |