Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.64 |
| ▸ | DRD4 | P21917 | 3/20 | 0.63 |
| ▸ | MOGAT2 | Q3SYC2 | 3/20 | 0.59 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298286 | 1.00 | CNR2 (0.64) | CNR2DRD4MOGAT2MGAT2MEN1 | |
| SCHEMBL2298750 | 1.00 | CNR2 (0.64) | CNR2DRD4MOGAT2MGAT2MEN1 | |
| SCHEMBL27405274 | 0.90 | CNR2 (0.77) | CNR2DRD4MOGAT2 | |
| SCHEMBL9523733 | 0.90 | CNR2 (0.77) | CNR2DRD4MOGAT2 | |
| SCHEMBL31116960 | 0.89 | CNR2 (0.51) | CNR2DRD4MOGAT2MGAT2MEN1 | |
| Hydrochloric Acid SCHEMBL8097089 | 0.88 | CNR2 (0.75) | CNR2DRD4MOGAT2 | |
| SCHEMBL2294344 | 0.87 | CNR2 (0.66) | CNR2DRD4MOGAT2 | |
| SCHEMBL2294156 | 0.87 | CNR2 (0.66) | CNR2DRD4MOGAT2 | |
| SCHEMBL24663585 | 0.86 | MOGAT2 (0.63) | CNR2DRD4MOGAT2MGAT2MEN1 | |
| SCHEMBL2290559 | 0.86 | MEN1 (0.58) | CNR2DRD4MOGAT2MGAT2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078392-A1 | 2-(ARYL-2-YL) MORPHOLINE AND DEUTERATED DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-05-11 | — | — | WO | disclosed |
| EP-1910320-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007011065-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-01-25 | — | — | WO | disclosed |
| CN-1049431-C | Morpholine and thiomorpholine tachykinin receptor antagonists | MERCK & CO INC (US) | 2000-02-16 | — | — | CN | disclosed |
| CN-1087902-A | Morpholine and thiomorpholine tachykinin receptor antagonists | MERCK & CO INC (US) | 1994-06-15 | — | — | CN | disclosed |