Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.77 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27405274 | 1.00 | CNR2 (0.77) | CNR2MOGAT2DRD4 | |
| Hydrochloric Acid SCHEMBL8097089 | 0.98 | CNR2 (0.75) | CNR2MOGAT2DRD4 | |
| SCHEMBL2294156 | 0.91 | CNR2 (0.66) | CNR2MOGAT2DRD4 | |
| SCHEMBL2294344 | 0.91 | CNR2 (0.66) | CNR2MOGAT2DRD4 | |
| SCHEMBL82233 | 0.90 | CNR2 (0.64) | CNR2MOGAT2DRD4 | |
| SCHEMBL2298286 | 0.90 | CNR2 (0.64) | CNR2MOGAT2DRD4 | |
| SCHEMBL4599689 | 0.90 | CNR2 (0.64) | CNR2MOGAT2DRD4 | |
| SCHEMBL323333 | 0.90 | CNR2 (0.64) | CNR2MOGAT2DRD4 | |
| SCHEMBL1438014 | 0.90 | CNR2 (0.64) | CNR2MOGAT2DRD4 | |
| SCHEMBL4480485 | 0.90 | CNR2 (0.72) | CNR2MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507863-A4 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | — | 1993-07-07 | — | — | EP | claimed |
| EP-0507863-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1992-10-14 | — | — | EP | claimed |
| WO-1991009594-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1991-07-11 | — | — | WO | claimed |
| CN-1106390-C | Polymorphic form of tachykinin receptor antagonist 2-(R)-(1-(R)-(3,5-bis(trifluoromethyl) phenyl) ethoxy)-3-(S)-(4-fluoro) phenyl-4-(3-5(oxo-1H,4H-1,2,4-triazolo methylmorpholine | MERCK & CO INC (US) | 2003-04-23 | — | — | CN | disclosed |