⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27592664 | 0.98 | TSHR (0.46) | — | |
| SCHEMBL27610762 | 0.98 | TSHR (0.46) | — | |
| SCHEMBL28753517 | 0.98 | TSHR (0.46) | — | |
| SCHEMBL1036813 | 0.93 | TSHR (0.55) | — | |
| SCHEMBL11740813 | 0.91 | TSHR (0.58) | — | |
| SCHEMBL4398855 | 0.91 | TSHR (0.58) | — | |
| SCHEMBL1447170 | 0.91 | TSHR (0.58) | — | |
| SCHEMBL1903671 | 0.91 | TSHR (0.58) | — | |
| SCHEMBL1356043 | 0.91 | TSHR (0.58) | — | |
| SCHEMBL9421274 | 0.91 | TSHR (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496331-A | Amygdalin derivative, specific modified product obtained from amygdalin derivative and preparation method of amygdalin derivative | 中国科学院上海药物研究所 | 2023-07-28 | — | — | CN | claimed |
| CN-107417719-B | Application of titanium chelate as reaction catalyst for synthesizing benzyl carbonate or diphenyl carbonate by ester exchange | 华东理工大学 | 2022-11-25 | — | — | CN | claimed |
| CN-109846740-A | Skin care compositions and methods and its preparation method and application | 江苏长泰药业有限公司 | 2019-06-07 | — | — | CN | claimed |
| CN-109821017-A | 5-ALA and iron chelating agent are preparing the application in antineoplastic combination drug | 天津医科大学 | 2019-05-31 | — | — | CN | claimed |
| CN-109721503-A | A kind of new synthetic method of 5-aminoketoglutarate hydrochloride | 于鹏 | 2019-05-07 | — | — | CN | claimed |
| CN-109336993-A | A kind of 5-ALA hyaluronic acid ester and its preparation method and application | 苏州蔓尔生物科技有限公司 | 2019-02-15 | — | — | CN | claimed |
| CN-109313388-A | Negative photosensitive composition | 普罗米鲁斯有限责任公司 | 2019-02-05 | — | — | CN | claimed |
| CN-105708788-B | A kind of preparation method of aminoguanidine hydrochloride ketone valeric acid nanometer emulsifiable paste | 济南梵康医疗科技有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-108379580-A | 5-aminolevulinic acid gel composition and application thereof | 四川大学 | 2018-08-10 | — | — | CN | claimed |
| CN-104894243-B | Nucleic acid aptamer probe, device and its application for tumour cell detection | 湖南大学 | 2018-01-16 | — | — | CN | claimed |
| CN-103301027-A | Cosmetic formulation with a dry skin feel | EVONIK INDUSTRIES AG | 2013-09-18 | — | — | CN | claimed |
| US-8309597-B2 | 1,1′-diadamantyl carboxylic acids, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-11-13 | — | — | US | claimed |
| EP-2438181-A2 | A METHOD FOR THE PREPARATION OF 2-KETO CARBOXYLIC ACID | Evonik Degussa GmbH (DE) | 2012-04-11 | — | — | EP | claimed |
| JP-2011529031-A | — | — | 2011-12-01 | — | — | JP | claimed |
| US-20110269736-A1 | 1,1'-Diadamantyl carboxylic acids, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2011-11-03 | — | — | US | claimed |
| CN-102216299-A | 2, 5-diamino-substituted pyrido [4, 3-d] pyrimidines as autotaxin inhibitors against cancer | MERCK PATENT GMBH | 2011-10-12 | — | — | CN | claimed |
| EP-2318355-A1 | 1,1'-DIADAMANTYL CARBOXYLIC ACIDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | Boehringer Ingelheim International GmbH (DE) | 2011-05-11 | — | — | EP | claimed |
| WO-2010139527-A2 | A METHOD FOR THE PREPARATION OF 2-KETO CARBOXYLIC ACID | EVONIK DEGUSSA GMBH (DE) | 2010-12-09 | — | — | WO | claimed |
| WO-2010010174-A1 | 1,1'-DIADAMANTYL CARBOXYLIC ACIDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-28 | — | — | WO | claimed |
| CN-101614744-A | The assay method of Ba Fei clam shell amino acid and fat-soluble chemical constitution | UNIV GUANGDONG OCEAN | 2009-12-30 | — | — | CN | claimed |