Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PAM | P19021 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28140931 | 1.00 | TSHR (0.58) | TSHRDGKALMNAPAMCES2 | |
| SCHEMBL1548895 | 1.00 | TSHR (0.58) | TSHRDGKALMNAPAMCES2 | |
| SCHEMBL9152744 | 1.00 | TSHR (0.58) | TSHRDGKALMNAPAMCES2 | |
| SCHEMBL594731 | 1.00 | TSHR (0.58) | TSHRDGKALMNAPAMCES2 | |
| SCHEMBL1356043 | 1.00 | TSHR (0.58) | TSHRDGKALMNAPAMCES2 | |
| SCHEMBL1903671 | 1.00 | TSHR (0.58) | TSHRDGKALMNAPAMCES2 | |
| SCHEMBL4398855 | 1.00 | TSHR (0.58) | TSHRDGKALMNAPAMCES2 | |
| SCHEMBL11740813 | 1.00 | TSHR (0.58) | TSHRDGKALMNAPAMCES2 | |
| SCHEMBL9421274 | 1.00 | TSHR (0.58) | TSHRDGKALMNAPAMCES2 | |
| SCHEMBL7524821 | 1.00 | TSHR (0.58) | TSHRDGKALMNAPAMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101132776-A | Stable tablet formulation of tetrahydrobiopterin | BIOMARIN PHARM INC (US) | 2008-02-27 | — | — | CN | claimed |
| US-20070270581-A1 | Stable Tablet Formulation | BIOMARIN PHARMACEUTICAL INC. (US) | 2007-11-22 | — | — | US | claimed |
| EP-1845952-A2 | STABLE TABLET FORMULATION OF TETRAHYDROBIOPTERIN | Biomarin Pharmaceutical Inc. (US) | 2007-10-24 | — | — | EP | claimed |
| WO-2006055511-A2 | STABLE TABLET FORMULATION OF TETRAHYDROBIOPTERIN | BIOMARIN PHARMACEUTICAL INC. (US) | 2006-05-26 | — | — | WO | claimed |
| US-5434276-A | Process for making N-acyl taurides | FINETEX, INC. (US) | 1995-07-18 | — | — | US | claimed |
| EP-0062362-B1 | STABILIZERS FOR VINYL HALIDE POLYMERS | FERRO CORPORATION (US) | 1985-07-24 | — | — | EP | claimed |
| CN-112159498-B | Fly ash water-based slurry for ceramic 3D printing and preparation method thereof | 武汉因泰莱激光科技有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-113751295-B | Preparation method and application of durable, super-smooth and super-hydrophobic surface | 浙江大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-110117510-B | Grease composition, clutch and electric window motor | NOK克鲁勃株式会社 | 2022-03-25 | — | — | CN | disclosed |
| CN-113751295-A | Preparation method and application of durable, super-smooth and super-hydrophobic surface | 浙江大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-107406792-B | Grease composition | NOK克鲁伯有限公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-106573304-B | Silver powder and method for producing same | 同和电子科技有限公司 | 2020-03-03 | — | — | CN | disclosed |
| US-10170213-B2 | Silver powder and method for producing same | DOWA ELECTRONICS MATERIALS CO., LTD. (JP) | 2019-01-01 | — | — | US | disclosed |
| EP-0017503-A2 | Gem-bis (hydroxymethyl) alcohols and mixtures thereof with diols, process for their preparation and a process for the preparation of polyurethanes therefrom | HENKEL CORPORATION (a Delaware corp.) (US) | 1980-10-15 | — | — | EP | disclosed |
| US-4222914-A | ZINC NEUTRALIZED | EXXON RESEARCH & ENGINEERING CO. (US) | 1980-09-16 | — | — | US | disclosed |
| US-4216344-A | High molecular weight polyol mixtures | HENKEL CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
| US-4216343-A | High molecular weight polyhydric alcohols | HENKEL CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
| EP-0002358-A2 | Process for forming a zinc neutralised sulphonated elastomeric polymer and composition thereof | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1979-06-13 | — | — | EP | disclosed |
| US-4083816-A | Acetoxymethyl derivatives of polyunsaturated fatty triglycerides as primary plasticizers for polyvinylchloride | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1978-04-11 | — | — | US | disclosed |
| US-4066585-A | THERMOPLASTIC BINDERS | SCHERING AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270581-A1 | Stable Tablet Formulation | QDPR, ADCYAP1R1, TPH1 | TSHR 1498/4885DGKA 4679/4885LMNA 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.