Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 9/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.33 |
| ▸ | ATP4A | P20648 | 1/20 | 0.32 |
| ▸ | ATP4B | P51164 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600359 | 0.87 | PPARD (0.42) | ERBB2MINK1PPARDFFAR1PPARA | |
| SCHEMBL4600629 | 0.87 | ERBB2 (0.48) | ERBB2MINK1PPARDFFAR1PPARG | |
| SCHEMBL4599523 | 0.86 | ERBB2 (0.45) | ERBB2MINK1PPARDFFAR1PPARG | |
| SCHEMBL4600209 | 0.86 | PRMT6 (0.41) | ERBB2MINK1PPARDFFAR1PPARG | |
| SCHEMBL4600401 | 0.83 | ERBB2 (0.51) | ERBB2MINK1PPARDFFAR1ATP4A | |
| SCHEMBL4600267 | 0.83 | ERBB2 (0.62) | ERBB2MINK1FFAR1HMOX1ATP4A | |
| SCHEMBL4601327 | 0.82 | ERBB2 (0.56) | ERBB2MINK1PPARDFFAR1PPARG | |
| SCHEMBL4592281 | 0.82 | ERBB2 (0.46) | ERBB2MINK1PPARDFFAR1HMOX1 | |
| SCHEMBL4600099 | 0.79 | ERBB2 (0.38) | ERBB2MINK1PPARDPPARGPPARA | |
| SCHEMBL4599907 | 0.79 | ERBB2 (0.46) | ERBB2MINK1PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912969-A1 | PHENYLPYRIDINE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017169-A1 | PHENYLPYRIDINE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-15 | — | — | WO | disclosed |