Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174737 | 0.93 | LMNA (0.46) | ALDH1A1TDP1L3MBTL1MCL1LMNA | |
| SCHEMBL2178830 | 0.89 | MAPK14 (0.42) | LMNASMN1; SMN2MAPK1 | |
| SCHEMBL2175907 | 0.88 | MAPK14 (0.41) | LMNASMN1; SMN2MAPK1 | |
| SCHEMBL2177627 | 0.88 | MAPK14 (0.41) | LMNASMN1; SMN2MAPK1 | |
| SCHEMBL2177043 | 0.88 | MAPK14 (0.41) | LMNASMN1; SMN2MAPK1 | |
| SCHEMBL2175595 | 0.86 | MAPK14 (0.43) | ALDH1A1TDP1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL2177234 | 0.82 | MAPK14 (0.44) | LMNASMN1; SMN2 | |
| SCHEMBL2177106 | 0.81 | MAPK14 (0.43) | ALDH1A1L3MBTL1 | |
| SCHEMBL2174902 | 0.81 | LMNA (0.42) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2175151 | 0.80 | LMNA (0.42) | ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948601-A1 | FAB I INHIBITOR AND PROCESS FOR PREPARING SAME | Crystalgenomics, Inc. (KR) | 2008-07-30 | — | — | EP | claimed |
| WO-2007043835-A1 | FAB I INHIBITOR AND PROCESS FOR PREPARING SAME | CRYSTALGENOMICS, INC. (KR) | 2007-04-19 | — | — | WO | claimed |