Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396389 | 0.87 | L3MBTL1 (0.56) | TDP1L3MBTL1KMT2ALMNAALDH1A1 | |
| Benzene SCHEMBL27414119 | 0.87 | L3MBTL1 (0.56) | TDP1L3MBTL1KMT2ALMNAALDH1A1 | |
| Bicarbonate SCHEMBL28144656 | 0.85 | L3MBTL1 (0.54) | TDP1L3MBTL1KMT2ALMNAALDH1A1 | |
| SCHEMBL27924002 | 0.85 | L3MBTL1 (0.54) | TDP1L3MBTL1KMT2ALMNAALDH1A1 | |
| SCHEMBL29024912 | 0.85 | L3MBTL1 (0.54) | TDP1L3MBTL1KMT2ALMNAALDH1A1 | |
| SCHEMBL17710384 | 0.85 | L3MBTL1 (0.54) | TDP1L3MBTL1KMT2ALMNAALDH1A1 | |
| Bicarbonate SCHEMBL19031939 | 0.85 | L3MBTL1 (0.54) | TDP1L3MBTL1KMT2ALMNAALDH1A1 | |
| SCHEMBL6803687 | 0.83 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3TDP1L3MBTL1 | |
| SCHEMBL14284024 | 0.83 | SMN1; SMN2 (0.55) | SLC6A2SLC6A4SLC6A3HTTSMN1; SMN2 | |
| SCHEMBL28787356 | 0.83 | MAPKAPK2 (0.46) | SLC6A3LMNAALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915361-A1 | ALKYLPYRIDYL QUINOLINES AS NK3 RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2008-04-30 | — | — | EP | claimed |
| WO-2007018466-A1 | ALKYLPYRIDYL QUINOLINES AS NK3 RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | claimed |
| CN-105917215-A | METHOD FOR ANALYSING A SAMPLE COMPRISING AT LEAST A FIRST AND A SECOND SCALE INHIBITOR | 凯米罗总公司 | 2016-08-31 | — | — | CN | disclosed |
| EP-1915361-A1 | ALKYLPYRIDYL QUINOLINES AS NK3 RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007018466-A1 | ALKYLPYRIDYL QUINOLINES AS NK3 RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | disclosed |