Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602176 | 0.90 | PPARG (0.74) | PPARG | |
| SCHEMBL4600034 | 0.84 | PPARG (0.73) | PPARGALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL4601167 | 0.83 | PPARG (0.69) | PPARGALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL4602045 | 0.83 | PPARG (0.71) | PPARGALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL4602698 | 0.83 | PPARG (0.66) | PPARGALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL4601036 | 0.83 | PPARG (0.68) | PPARGALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL4601543 | 0.82 | PPARG (0.67) | PPARGALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL4529260 | 0.82 | PPARG (0.61) | PPARG | |
| SCHEMBL4601660 | 0.81 | PPARG (0.64) | PPARGALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL4602510 | 0.81 | PPARG (0.59) | PPARGALDH1A1SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |