SCHEMBL4600933

SCHEMBL4600933

C[C@@H](N)C(=O)Oc1cccc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
HSD17B10 Q99714 3/20 0.57
PGR P06401 1/20 0.57
GAA P10253 1/20 0.57
PTGS1 P23219 1/20 0.57
MAPK1 P28482 1/20 0.57
KMT2A Q03164 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MEN1 O00255 1/20 0.51
RAB9A P51151 1/20 0.51
CARM1 Q86X55 1/20 0.50
PRMT6 Q96LA8 1/20 0.50
KDM4E B2RXH2 3/20 0.47
HPGD P15428 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
MMP2 P08253 1/20 0.46
OGG1 O15527 1/20 0.45
FABP7 O15540 3/20 0.44
FABP3 P05413 3/20 0.44
FABP5 Q01469 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246709 1.00 ALDH1A1 (0.57) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL8458747 1.00 ALDH1A1 (0.57) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL10714230 0.86 ALDH1A1 (0.60) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL10713841 0.86 ALDH1A1 (0.60) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL27660507 0.85 ALDH1A1 (0.58) ALDH1A1HSD17B10PGRGAAPTGS1
Hydrochloric Acid SCHEMBL27504502 0.85 ALDH1A1 (0.58) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL11991237 0.83 ALDH1A1 (0.57) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL10770213 0.83 ALDH1A1 (0.57) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL6103148 0.83 ALDH1A1 (0.50) ALDH1A1HSD17B10PGRGAAPTGS1
Leucine SCHEMBL7633145 0.83 CARM1 (0.43) ALDH1A1HSD17B10PGRGAAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254771-B2 Detection of microbes in a sample EDBERG STEPHEN C (US) 2000-02-02 EP claimed
US-5429933-A Targets for microbes EDBERG STEPHEN C (US) 1995-07-04 US claimed
US-4925789-A COLORIMETRIC ANALYSIS EDBERG STEPHEN C (US) 1990-05-15 US claimed
EP-0254771-A2 Detection of microbes in a sample Edberg, Stephen C. (US) 1988-02-03 EP claimed
EP-1528106-B1 Medium for detecting target microbes in a sample IDEXX LAB INC (US) 2008-04-23 EP disclosed
EP-1403378-B1 Medium for detecting target microbes in a sample IDEXX LAB INC (US) 2008-02-27 EP disclosed
EP-1528106-A1 Medium for detecting target microbes in a sample IDEXX LABORATORIES, INC. (US) 2005-05-04 EP disclosed
US-6783950-B2 COMBINING LIQUID WATER SAMPLE AND A POWDERED MEDIUM HAVING NUTRIENT INDICATOR; INCUBATING THE MIXTURE FOR A TIME SUFFICIENT TO PRODUCE A DETECTABLE COLOR SIGNAL INDICATIVE OF PRESENCE OR ABSENCE OF TARGET MICROBE; OBSERVING SIGNAL EDBERG STEPHEN C (US) 2004-08-31 US disclosed
US-6730496-B2 NUTRIENT INDICATORS TO SUPPORT GROWTH OF TARGET MICROBE BEING OPERABLE TO ALTER A DETECTABLE CHARACTERISTIC WHEN METABOLIZED EDBERG STEPHEN C (US) 2004-05-04 US disclosed
EP-1403378-A2 Medium for detecting target microbes in a sample IDEXX LABORATORIES, INC. (US) 2004-03-31 EP disclosed
US-20030203422-A1 METHOD OF DETECTING A MICROBE IN A LIQUID WATER SAMPLE EDBERG STEPHEN C (US) 2003-10-30 US disclosed
US-20030190694-A1 Detection of first generation environmental sourced microbes in an environmentally-derived sample EDBERG STEPHEN C (US) 2003-10-09 US disclosed
US-20020031796-A1 Method and composition for detecting bacterial contamination in food products BIOCONTROL SYSTEMS, INC. 2002-03-14 US disclosed
US-6329166-B1 A NUTRIENT INDICATOR HAVING A MODIFIED NUTRIENT THAT IS ACTIVATED TO ALTER THE SAMPLE ONLY IF THE SPECIFIC NUTRIENT IS METABOLIZED BY THE TARGET MICROBE AND CAN BE DETECTED; FOR FOOD AND WATER TESTING EDBERG STEPHEN C (US) 2001-12-11 US disclosed
EP-0254771-B2 Detection of microbes in a sample EDBERG STEPHEN C (US) 2000-02-02 EP disclosed
US-5780259-A Medium and method for detecting a target microbe EDBERG STEPHEN C (US) 1998-07-14 US disclosed
US-5610029-A BACTERIA CULTURE, NUTRIENT INDICATOR IDEXX LABORATORIES, INC. (US) 1997-03-11 US disclosed
US-5429933-A Targets for microbes EDBERG STEPHEN C (US) 1995-07-04 US disclosed
US-4925789-A COLORIMETRIC ANALYSIS EDBERG STEPHEN C (US) 1990-05-15 US disclosed
EP-0254771-A2 Detection of microbes in a sample Edberg, Stephen C. (US) 1988-02-03 EP disclosed