Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AOC2 | O75106 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1575681 | 0.88 | GPR119 (0.52) | GPR119 | |
| SCHEMBL1575683 | 0.88 | GPR119 (0.52) | GPR119 | |
| SCHEMBL3178807 | 0.77 | ESR2 (0.46) | ALDH1A1L3MBTL1ITGB3ITGA2B | |
| SCHEMBL3178811 | 0.77 | ESR2 (0.46) | ALDH1A1L3MBTL1ITGB3ITGA2B | |
| SCHEMBL2430940 | 0.76 | GPR119 (0.62) | GPR119AOC2 | |
| SCHEMBL1575647 | 0.75 | GPR119 (0.43) | GPR119 | |
| SCHEMBL1575646 | 0.75 | GPR119 (0.43) | GPR119 | |
| SCHEMBL1576038 | 0.73 | GPR119 (0.43) | GPR119 | |
| SCHEMBL1575094 | 0.72 | GPR119 (0.64) | GPR119 | |
| SCHEMBL1575093 | 0.72 | GPR119 (0.64) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910290-A2 | GPCR AGONISTS | Prosidion Limited (GB) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007003962-A2 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |