Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 12/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600365 | 0.91 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL4600716 | 0.86 | PDE4D (0.59) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL4601471 | 0.85 | PDE4D (0.60) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL8466183 | 0.85 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL4602843 | 0.84 | CFD (0.56) | KMT2AKDM4EAPAF1RECQLCASP6 | |
| SCHEMBL4602161 | 0.81 | PDE4D (0.62) | PDE4APDE4BPDE4CPDE4DSYK | |
| SCHEMBL8465687 | 0.81 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL4601485 | 0.79 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DSYK | |
| SCHEMBL7444846 | 0.78 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL4601903 | 0.78 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | claimed |
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | claimed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | claimed |
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | PDE4A 1576/4885PDE4B 1807/4885PDE4C 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.