SCHEMBL4601417

SCHEMBL4601417

O=C(CI)NCCc1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
NQO2 P16083 1/20 0.45
MTNR1A P48039 11/20 0.44
MTNR1B P49286 5/20 0.44
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
ITPR1 Q14643 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7099062 0.92 MEN1 (0.59) MEN1KMT2ANQO2MTNR1AMTNR1B
SCHEMBL1801575 0.85 KMT2A (0.50) MEN1KMT2ANQO2KDM4EALDH1A1
SCHEMBL27575163 0.78 NQO2 (0.55) NQO2MTNR1AMTNR1B
SCHEMBL31713966 0.77 KMT2A (0.66) MEN1KMT2AMTNR1AMTNR1BKDM4E
SCHEMBL29367001 0.76 MEN1 (0.60) MEN1KMT2AMTNR1AMTNR1BITPR1
SCHEMBL17440482 0.76 MEN1 (0.60) MEN1KMT2AMTNR1AMTNR1BITPR1
SCHEMBL31036784 0.75 MEN1 (0.55) MEN1KMT2AMTNR1AMTNR1BITPR1
SCHEMBL16011252 0.75 MEN1 (0.55) MEN1KMT2AMTNR1AMTNR1BITPR1
SCHEMBL16414928 0.74 KMT2A (0.62) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL19786485 0.74 KMT2A (0.67) MEN1KMT2AMTNR1AMTNR1BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1335984-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENSOR COMPRISING A MODIFIED COENZYME A- AND ACYL-COA BINDING PROTEIN (ACBP) Biosensor APS (DK) 2003-08-20 EP claimed
US-20020142347-A1 Biosensor BIOSENSOR APS (DK) 2002-10-03 US claimed
WO-2002061096-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENS OR COMPRISING A MODIFIED COENZYME A- AND ACYL- BINDING PROTEIN (ACBP) BIOSENSOR APS (DK) 2002-08-08 WO claimed
US-10851403-B2 Cyclin-dependent kinase substrate SYSMEX CORPORATION (JP) 2020-12-01 US disclosed
US-20180334702-A1 CYCLIN-DEPENDENT KINASE SUBSTRATE SYSMEX CORPORATION (JP) 2018-11-22 US disclosed
EP-3404038-A1 CYCLIN-DEPENDENT KINASE SUBSTRATE SYSMEX CORPORATION (JP) 2018-11-21 EP disclosed
US-20150276740-A1 METHOD FOR DETERMINING KINASE ACTIVITY SYSMEX CORPORATION (JP) 2015-10-01 US disclosed
US-8309298-B2 Method for detecting protein SYSMEX CORPORATION (JP) 2012-11-13 US disclosed
EP-1609854-B1 Method for determining activity of cell cycle regulatory factor and method for diagnosing cancer using the same SYSMEX CORP (JP) 2008-04-30 EP disclosed
US-7338774-B2 Method for determining activity of cell cycle regulatory factor and method for diagnosing cancer using the same SYSMEX CORPORATION (JP) 2008-03-04 US disclosed
US-20070264624-A1 METHOD FOR DETERMINING ACTIVITY OF CELL CYCLE REGULATORY FACTOR AND METHOD FOR DIAGNOSING CANCER USING THE SAME ISHIHARA HIDEKI 2007-11-15 US disclosed
EP-1767943-A2 Method for detecting analyte in sample Sysmex Corporation (JP) 2007-03-28 EP disclosed
EP-1609854-A1 Method for determining activity of cell cycle regulatory factor and method for diagnosing cancer using the same Sysmex Corporation (JP) 2005-12-28 EP disclosed
EP-0810291-B1 PROBE FOR USE IN NUCLEIC ACID ANALYSIS AND DETECTING METHOD BASED ON EXCIMER FLUORESCENCE HAMAMATSU PHOTONICS KK (JP) 2003-10-29 EP disclosed
EP-1335984-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENSOR COMPRISING A MODIFIED COENZYME A- AND ACYL-COA BINDING PROTEIN (ACBP) Biosensor APS (DK) 2003-08-20 EP disclosed
US-20020164673-A1 Method for determining activity of cell cycle regulatory factor and method for diagnosing cancer using the same SYSMEX CORPORATION (JP) 2002-11-07 US disclosed
US-20020142347-A1 Biosensor BIOSENSOR APS (DK) 2002-10-03 US disclosed
EP-1233060-A2 Method for determining activity of cell cycle regulatory factor and method for diagnosing cancer using the same Sysmex Corporation (JP) 2002-08-21 EP disclosed
WO-2002061096-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENS OR COMPRISING A MODIFIED COENZYME A- AND ACYL- BINDING PROTEIN (ACBP) BIOSENSOR APS (DK) 2002-08-08 WO disclosed
EP-0810291-A1 PROBE FOR USE IN NUCLEIC ACID ANALYSIS AND DETECTING METHOD The society for Techno-Innovation of Agriculture, Forestry and Fisheries (JP) 1997-12-03 EP disclosed