SCHEMBL1801575

SCHEMBL1801575

O=C(CI)NCc1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 4/20 0.45
HPGD P15428 4/20 0.45
MAPT P10636 2/20 0.45
FAAH O00519 1/20 0.43
POLB P06746 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP1A2 P05177 1/20 0.40
GLA P06280 1/20 0.40
CYP2D6 P10635 1/20 0.40
NQO2 P16083 1/20 0.40
F10 P00742 1/20 0.39
HTT P42858 1/20 0.39
GAA P10253 1/20 0.38
TERT O14746 1/20 0.36
CA2 P00918 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14940250 0.88 KMT2A (0.53) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL4601417 0.85 MEN1 (0.55) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL2009382 0.85 KMT2A (0.50) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL12571772 0.85 KMT2A (0.50) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL20422761 0.84 KMT2A (0.49) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL7099062 0.83 MEN1 (0.59) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL24700650 0.82 KMT2A (0.48) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL14940077 0.82 KMT2A (0.67) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL27931462 0.81 ALDH1A1 (0.55) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL19785408 0.81 KMT2A (0.50) KMT2AMEN1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080138908-A1 Mass Spectrometry THE NOGUCHI INSTITUTE (JP) 2008-06-12 US claimed
EP-1335984-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENSOR COMPRISING A MODIFIED COENZYME A- AND ACYL-COA BINDING PROTEIN (ACBP) Biosensor APS (DK) 2003-08-20 EP claimed
US-20020142347-A1 Biosensor BIOSENSOR APS (DK) 2002-10-03 US claimed
WO-2002061096-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENS OR COMPRISING A MODIFIED COENZYME A- AND ACYL- BINDING PROTEIN (ACBP) BIOSENSOR APS (DK) 2002-08-08 WO claimed
US-10851403-B2 Cyclin-dependent kinase substrate SYSMEX CORPORATION (JP) 2020-12-01 US disclosed
CN-108948135-A Cell cycle protein dependent kinase substrate 希森美康株式会社 2018-12-07 CN disclosed
US-20180334702-A1 CYCLIN-DEPENDENT KINASE SUBSTRATE SYSMEX CORPORATION (JP) 2018-11-22 US disclosed
EP-3404038-A1 CYCLIN-DEPENDENT KINASE SUBSTRATE SYSMEX CORPORATION (JP) 2018-11-21 EP disclosed
US-10126467-B2 Signal enhancement by silk photonic crystals TUFTS UNIVERSITY (US) 2018-11-13 US disclosed
EP-2752659-B1 MALDI MASS ANALYSIS METHOD THE NOGUCHI INST (JP) 2017-10-18 EP disclosed
US-20150276740-A1 METHOD FOR DETERMINING KINASE ACTIVITY SYSMEX CORPORATION (JP) 2015-10-01 US disclosed
CN-104950110-A Method for determining kinase activity, ATP derivative, and use and manufacture method thereof SYSMEX CORP 2015-09-30 CN disclosed
EP-0810291-B1 PROBE FOR USE IN NUCLEIC ACID ANALYSIS AND DETECTING METHOD BASED ON EXCIMER FLUORESCENCE HAMAMATSU PHOTONICS KK (JP) 2003-10-29 EP disclosed
EP-1335984-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENSOR COMPRISING A MODIFIED COENZYME A- AND ACYL-COA BINDING PROTEIN (ACBP) Biosensor APS (DK) 2003-08-20 EP disclosed
US-20020164673-A1 Method for determining activity of cell cycle regulatory factor and method for diagnosing cancer using the same SYSMEX CORPORATION (JP) 2002-11-07 US disclosed
WO-2002079216-A1 LABELED OLIGONUCLEOTIDES, METHODS FOR MAKING SAME, AND COMPOUNDS USEFUL THEREFOR ISIS PHARMACEUTICALS, INC. (US) 2002-10-10 WO disclosed
US-20020142347-A1 Biosensor BIOSENSOR APS (DK) 2002-10-03 US disclosed
EP-1233060-A2 Method for determining activity of cell cycle regulatory factor and method for diagnosing cancer using the same Sysmex Corporation (JP) 2002-08-21 EP disclosed
WO-2002061096-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENS OR COMPRISING A MODIFIED COENZYME A- AND ACYL- BINDING PROTEIN (ACBP) BIOSENSOR APS (DK) 2002-08-08 WO disclosed
EP-0810291-A1 PROBE FOR USE IN NUCLEIC ACID ANALYSIS AND DETECTING METHOD The society for Techno-Innovation of Agriculture, Forestry and Fisheries (JP) 1997-12-03 EP disclosed