Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 12/20 | 0.75 |
| ▸ | ICAM1 | P05362 | 12/20 | 0.75 |
| ▸ | ITGAL | P20701 | 12/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | FPR2 | P25090 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154691 | 1.00 | ITGB2 (0.75) | ITGB2ICAM1ITGALPOLBMAPT | |
| SCHEMBL4601432 | 0.87 | ITGB2 (0.56) | ITGB2ICAM1ITGAL | |
| SCHEMBL15145334 | 0.86 | ITGB2 (0.84) | ITGB2ICAM1ITGALPOLBMAPT | |
| SCHEMBL15145346 | 0.84 | ITGB2 (0.81) | ITGB2ICAM1ITGALPOLBMAPT | |
| SCHEMBL15145352 | 0.80 | ITGB2 (0.67) | ITGB2ICAM1ITGALMAPTHPGD | |
| SCHEMBL11873894 | 0.80 | ITGB2 (0.73) | ITGB2ICAM1ITGALFPR2ERAP2 | |
| SCHEMBL21623645 | 0.80 | ITGB2 (0.73) | ITGB2ICAM1ITGALFPR2ERAP2 | |
| SCHEMBL1358031 | 0.80 | ITGB2 (0.80) | ITGB2ICAM1ITGALPOLBMAPT | |
| SCHEMBL1358036 | 0.80 | ITGB2 (0.80) | ITGB2ICAM1ITGALPOLBMAPT | |
| SCHEMBL14557598 | 0.79 | MAPT (0.49) | ITGB2ICAM1ITGALPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | ITGB2 4080/4885ICAM1 4413/4885ITGAL 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.