Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 10/20 | 0.73 |
| ▸ | ICAM1 | P05362 | 10/20 | 0.73 |
| ▸ | ITGAL | P20701 | 10/20 | 0.73 |
| ▸ | FPR2 | P25090 | 1/20 | 0.72 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.72 |
| ▸ | MMP2 | P08253 | 1/20 | 0.66 |
| ▸ | MMP9 | P14780 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11873894 | 1.00 | ITGB2 (0.73) | ITGB2ICAM1ITGALFPR2ERAP2 | |
| SCHEMBL30616778 | 0.92 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2CA12 | |
| SCHEMBL9466705 | 0.92 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2CA12 | |
| SCHEMBL5259129 | 0.92 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2CA12 | |
| SCHEMBL5191302 | 0.92 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2CA12 | |
| SCHEMBL11870861 | 0.91 | ERAP2 (0.76) | ITGB2ICAM1ITGALERAP2CA12 | |
| SCHEMBL22206878 | 0.90 | ITGB2 (0.77) | ITGB2ICAM1ITGALERAP2CA12 | |
| SCHEMBL22206876 | 0.90 | ITGB2 (0.77) | ITGB2ICAM1ITGALERAP2CA12 | |
| SCHEMBL9828348 | 0.89 | ERAP2 (0.74) | ITGB2ICAM1ITGALERAP2CA12 | |
| SCHEMBL9828342 | 0.89 | ERAP2 (0.74) | ITGB2ICAM1ITGALERAP2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014726-A1 | TREATMENT FOR LIVER REGENERATION | XENEXUS PHARMACEUTICALS PTY. LTD. (AU) | 2020-01-23 | — | — | WO | disclosed |