Acrylonitrile

Acrylonitrile

SCHEMBL460151

C=CC#N.C=CC(=O)OCC1CO1.C=CCOC(=O)C=C

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
TP53 P04637 3/20 0.36
CYP3A4 P08684 2/20 0.36
MGLL Q99685 3/20 0.36
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
TSHR P16473 5/20 0.32
HIF1A Q16665 2/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylonitrile SCHEMBL9562022 0.93 ALDH1A1 (0.45) ALDH1A1TP53CYP3A4MGLLTSHR
SCHEMBL27383461 0.91 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MGLLMAPT
Acrylonitrile SCHEMBL460413 0.89 ALDH1A1 (0.56) ALDH1A1TP53CYP3A4MGLLTSHR
Acrylonitrile SCHEMBL459164 0.89 ALDH1A1 (0.59) ALDH1A1TP53CYP3A4TSHR
Acrylic Acid SCHEMBL27665480 0.88 ALDH1A1 (0.41) ALDH1A1TP53CYP3A4MGLLTSHR
Water SCHEMBL10496050 0.84 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MGLLTSHR
SCHEMBL29850839 0.83 ALDH1A1 (0.53) ALDH1A1TP53CYP3A4MGLLTSHR
SCHEMBL17692 0.83
SCHEMBL15082542 0.83
Acrylonitrile SCHEMBL277295 0.83 TSHR (0.43) ALDH1A1TP53CYP3A4MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US claimed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP claimed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US claimed
US-11203192-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2021-12-21 US disclosed
US-10844184-B2 Matte finish polyimide films and methods relating thereto DUPONT ELECTRONICS, INC. (US) 2020-11-24 US disclosed
US-20190263099-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-08-29 US disclosed
US-10336045-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2019-07-02 US disclosed
US-20180163006-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-06-14 US disclosed
US-9926415-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2018-03-27 US disclosed
US-20170174950-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2017-06-22 US disclosed
US-9631054-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2017-04-25 US disclosed
US-20110287243-A1 MULTILAYER FILM FOR ELECTRONIC CIRCUITRY APPLICATIONS AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-24 US disclosed
US-20110177321-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-21 US disclosed
WO-2011019899-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 WO disclosed
US-20110039085-A1 PIGMENTED POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 US disclosed
WO-2011017291-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-10 WO disclosed
WO-2010101822-A1 MULTILAYER FILM FOR ELECTRONIC CIRCUITRY APPLICATIONS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-10 WO disclosed
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US disclosed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP disclosed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US disclosed