Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSHR | P23945 | 15/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394638 | 0.94 | FSHR (0.53) | FSHRBRAFMAPK14 | |
| SCHEMBL3391456 | 0.92 | FSHR (0.53) | FSHRBRAFMAPK14 | |
| SCHEMBL3394823 | 0.90 | FSHR (0.65) | FSHR | |
| SCHEMBL3396761 | 0.88 | FSHR (0.51) | FSHRRAB9A | |
| SCHEMBL3393357 | 0.86 | FSHR (0.56) | FSHR | |
| SCHEMBL3398201 | 0.85 | FSHR (0.59) | FSHR | |
| SCHEMBL3396056 | 0.85 | FSHR (0.55) | FSHR | |
| SCHEMBL3425195 | 0.85 | FSHR (0.58) | FSHR | |
| SCHEMBL3396766 | 0.84 | FSHR (0.58) | FSHRRAB9AHSD17B10 | |
| SCHEMBL3426374 | 0.84 | FSHR (0.49) | FSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578727-B1 | TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS FSH RECEPTOR MODULATORS | ORGANON NV (NL) | 2008-04-16 | — | — | EP | disclosed |