Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSHR | P23945 | 16/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398201 | 0.91 | FSHR (0.59) | FSHRKDRL3MBTL1ALDH1A1MAPT | |
| SCHEMBL3394823 | 0.91 | FSHR (0.65) | FSHRKDRALDH1A1 | |
| SCHEMBL3425195 | 0.91 | FSHR (0.58) | FSHRKDRL3MBTL1 | |
| SCHEMBL3393357 | 0.89 | FSHR (0.56) | FSHRKDRKDM4EALDH1A1 | |
| SCHEMBL3396056 | 0.88 | FSHR (0.55) | FSHRKDRL3MBTL1ALDH1A1MAPT | |
| SCHEMBL4600077 | 0.87 | FSHR (0.54) | FSHRKDR | |
| SCHEMBL3393344 | 0.85 | FSHR (0.59) | FSHRKDR | |
| SCHEMBL3397813 | 0.85 | FSHR (0.54) | FSHRKDRALDH1A1 | |
| SCHEMBL4601614 | 0.84 | FSHR (0.56) | FSHRRAB9AHSD17B10 | |
| SCHEMBL3391456 | 0.84 | FSHR (0.53) | FSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674909-B2 | Biphenyl-4-carboxylic acid {1-acetyl-4-[4-(2-dimethylammo-ethoxy-phenyl]-2,2,4-trimethyl-1,2,3,4-tetrahydro-quinolin-6-yl}-amide; fertility regulation; follicle stimulating hormone (FSH) | N.V. ORGANON (NL) | 2010-03-09 | — | — | US | disclosed |
| EP-1578727-B1 | TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS FSH RECEPTOR MODULATORS | ORGANON NV (NL) | 2008-04-16 | — | — | EP | disclosed |
| US-20060167047-A1 | Tetrahydorquinoline derivatives and their use as fsh receptor modulators | MERCK SHARP & DOHME B.V. (NL) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167047-A1 | Tetrahydorquinoline derivatives and their use as fsh receptor modulators | FSHR, GNRHR, LHCGR | FSHR 1/4885KDR 254/4885L3MBTL1 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.