Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.54 |
| ▸ | GAA | P10253 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2350760 | 0.79 | MAPT (0.59) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL4235980 | 0.73 | MAPT (0.52) | MAPTMEN1KMT2AHCRTR1LMNA | |
| SCHEMBL2344153 | 0.73 | MAPT (0.63) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL2351047 | 0.73 | MAPT (0.65) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL3989900 | 0.72 | MAPT (0.56) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL2352743 | 0.71 | MAPT (0.58) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL2906711 | 0.70 | SMN1; SMN2 (0.61) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL2912400 | 0.70 | SMN1; SMN2 (0.61) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL14083188 | 0.70 | MAPT (0.52) | MAPTGAAMEN1KMT2AHCRTR1 | |
| SCHEMBL2346099 | 0.70 | MAPK14 (0.60) | MAPTGAAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940786-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | Arrow Therapeutics Limited (GB) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007031791-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2007-03-22 | — | — | WO | disclosed |