Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MTOR | P42345 | 3/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4245782 | 0.88 | SMN1; SMN2 (0.54) | MAPTL3MBTL1SMN1; SMN2WNT3AALDH1A1 | |
| SCHEMBL3962780 | 0.84 | MAPT (0.54) | MAPTL3MBTL1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL2344153 | 0.75 | MAPT (0.63) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL4601644 | 0.73 | MAPT (0.54) | MAPTL3MBTL1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL2352743 | 0.73 | MAPT (0.58) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL4237879 | 0.72 | SMN1; SMN2 (0.55) | MAPTL3MBTL1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL3121764 | 0.71 | ALDH1A1 (0.57) | MAPTL3MBTL1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL2351047 | 0.71 | MAPT (0.65) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL3955448 | 0.71 | RAB9A (0.56) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL4240335 | 0.70 | MAPT (0.55) | MAPTL3MBTL1SMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034390-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |