SCHEMBL4601647

SCHEMBL4601647

N#Cc1nc2ccccc2nc1C#N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.53
ALDH1A1 P00352 5/20 0.50
KDM4E B2RXH2 4/20 0.50
USP8 P40818 1/20 0.47
USP7 Q93009 1/20 0.47
USP47 Q96K76 1/20 0.47
PSMB8 P28062 2/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CASP1 P29466 1/20 0.44
CYP2C19 P33261 1/20 0.44
CASP7 P55210 1/20 0.44
GAA P10253 2/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31143803 1.00 MAPT (0.53) MAPTALDH1A1KDM4EUSP8USP7
SCHEMBL12630108 0.84 ALDH1A1 (0.45) MAPTALDH1A1KDM4EPSMB8CYP1A2
SCHEMBL11693530 0.84 ALDH1A1 (0.42) MAPTALDH1A1KDM4EUSP8USP7
SCHEMBL1128621 0.84 MAPT (0.58) MAPTALDH1A1KDM4EUSP8PSMB8
SCHEMBL29424973 0.84 MAPT (0.58) MAPTALDH1A1KDM4EUSP8PSMB8
SCHEMBL4322949 0.84 TDP1 (0.58) MAPTALDH1A1KDM4EUSP8USP7
SCHEMBL22931800 0.84 ALDH1A1 (0.42) MAPTALDH1A1KDM4EUSP8USP7
SCHEMBL12340149 0.82 ALDH1A1 (0.41) MAPTALDH1A1KDM4EUSP8USP7
SCHEMBL1993804 0.79 KDM4E (0.57) MAPTALDH1A1KDM4EPSMB8CASP1
SCHEMBL19169688 0.79 KDM4E (0.38) MAPTALDH1A1KDM4EUSP8USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217500-B Cyano quinoxaline red light thermal excitation delayed fluorescent material, synthetic method and application thereof 黑龙江大学 2025-05-16 CN claimed
CN-116217500-A Cyano quinoxaline red light thermal excitation delayed fluorescent material, synthetic method and application thereof 黑龙江大学 2023-06-06 CN claimed
CN-113200929-B Cyano quinoxaline red light thermal excitation delayed fluorescent material, synthetic method and application thereof 黑龙江大学 2023-04-28 CN claimed
CN-101282946-B Cysteine protease inhibitors and their therapeutic use HYBRIGENICS SA 2013-08-14 CN claimed
CN-100560652-C Heterocyclic colorants based on diaza benzo isoindole CLARIANT PRODUKTE DEUTSCHLAND (DE) 2009-11-18 CN claimed
CN-101282946-A Novel cysteine protease inhibitors and their therapeutic use HYBRIGENICS SA (FR) 2008-10-08 CN claimed
EP-1639047-B1 HETEROCYCLIC COLORANTS BASED ON DIAZABENZOISOINDOLES CLARIANT PRODUKTE DEUTSCHLAND (DE) 2008-04-23 EP claimed
US-20070264600-A1 Heterocyclic Colorants Based on Diazabenzoisoindoles CLARIANT GMBH (DE) 2007-11-15 US claimed
CN-1802419-A Heterocyclic colorants based on diazabenzoisoindoles CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-07-12 CN claimed
EP-1639047-A1 HETEROCYCLIC COLORANTS BASED ON DIAZABENZOISOINDOLES Clariant Produkte (Deutschland) GmbH (DE) 2006-03-29 EP claimed
WO-2004108836-A1 HETEROCYCLIC COLORANTS BASED ON DIAZABENZOISOINDOLES CLARIANT GMBH (DE) 2004-12-16 WO claimed
JP-3009882-A None JP disclosed
WO-2026082222-A1 FUSED QUINOXALINE-2,3-DICARBONITRILE DERIVATIVES, THEIR PHOTOCHEMICAL SYNTHESIS AND USE THEREOF UNIVERZITA PARDUBICE (CZ) 2026-04-23 WO disclosed
CN-116217500-B Cyano quinoxaline red light thermal excitation delayed fluorescent material, synthetic method and application thereof 黑龙江大学 2025-05-16 CN disclosed
CN-114805741-B Polymer luminescent material based on polyurethane main chain, and preparation method and application thereof 安徽秀朗新材料科技有限公司 2023-10-13 CN disclosed
JP-H039882-A OPTICAL DATA RECORDING MEDIUM SANYO CHEM IND LTD 1991-01-17 JP disclosed
EP-0356971-A1 Tetraazaporphyrins and optical recording medium BASF Aktiengesellschaft (DE) 1990-03-07 EP disclosed
EP-0344891-A2 Tetraazaporphin, process for producing the same, as well as optical recording media using the same and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1989-12-06 EP disclosed
US-4460403-A 2,3-Dicyano 6 phenyl pyrazine herbicides KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) 1984-07-17 US disclosed
US-4259489-A PREEMERGENCE AND POSTEMERGENCE HERBICIDES KYOWA GAS CHEMICAL INDUSTRY CO. LTD. (JP) 1981-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070264600-A1 Heterocyclic Colorants Based on Diazabenzoisoindoles DDT, CDK4, CDK13 MAPT 3308/4885ALDH1A1 120/4885KDM4E 2063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.