Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | MC1R | Q01726 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10306285 | 0.82 | GPBAR1 (0.42) | MC4RFABP7FABP5PKMGPBAR1 | |
| SCHEMBL13542623 | 0.81 | GRM5 (0.40) | MC4RFABP7FABP5PKMGPBAR1 | |
| SCHEMBL6192353 | 0.80 | MC4R (0.48) | MC4RKCNH2MC1RPRCP | |
| SCHEMBL1920424 | 0.79 | MC4R (0.54) | MC4RKCNH2HTR2CPRCP | |
| SCHEMBL12533727 | 0.79 | MC4R (0.54) | MC4RKCNH2HTR2CPRCP | |
| SCHEMBL29327388 | 0.79 | MC4R (0.54) | MC4RKCNH2HTR2CPRCP | |
| SCHEMBL1921102 | 0.79 | MC4R (0.54) | MC4RKCNH2HTR2CPRCP | |
| SCHEMBL3170784 | 0.79 | MC4R (0.56) | MC4RKCNH2HTR2CPRCP | |
| SCHEMBL3160522 | 0.79 | MC4R (0.56) | MC4RKCNH2HTR2CPRCP | |
| SCHEMBL29904543 | 0.79 | MC4R (0.56) | MC4RKCNH2HTR2CPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912968-A1 | PIPERIDINOYL-PYRROLIDINE AND PIPERIDINOYL-PIPERIDINE COMPOUNDS | Pfizer Limited (GB) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007015162-A1 | PIPERIDINOYL-PYRROLIDINE AND PIPERIDINOYL-PIPERIDINE COMPOUNDS | PFIZER LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |