Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | PRCP | P42785 | 8/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921102 | 1.00 | MC4R (0.54) | MC4RKCNH2PRCPHTR2CFPR1 | |
| SCHEMBL12533727 | 1.00 | MC4R (0.54) | MC4RKCNH2PRCPHTR2CFPR1 | |
| SCHEMBL1920424 | 1.00 | MC4R (0.54) | MC4RKCNH2PRCPHTR2CFPR1 | |
| SCHEMBL14610892 | 0.88 | MC4R (0.46) | MC4RKCNH2PRCPFPR1FPR2 | |
| SCHEMBL1920197 | 0.87 | FPR1 (0.48) | MC4RKCNH2FPR1FPR2 | |
| SCHEMBL21036774 | 0.87 | FPR1 (0.44) | MC4RKCNH2PRCPHTR2CFPR1 | |
| SCHEMBL21036775 | 0.87 | FPR1 (0.44) | MC4RKCNH2PRCPHTR2CFPR1 | |
| Hydrochloric Acid SCHEMBL20994326 | 0.86 | FPR1 (0.43) | MC4RKCNH2PRCPHTR2CFPR1 | |
| SCHEMBL23951714 | 0.83 | MC4R (0.41) | MC4RKCNH2 | |
| SCHEMBL3160522 | 0.83 | MC4R (0.56) | MC4RKCNH2PRCPHTR2CFPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238281-A1 | PIPERAZINE DERIVATIVES AND APPLICATION THEREOF | GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS CO., LTD. BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY (CN) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238281-A1 | PIPERAZINE DERIVATIVES AND APPLICATION THEREOF | AQP3, SLC6A7, ABCG2 | MC4R 2367/4885KCNH2 265/4885PRCP 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.