Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.60 |
| ▸ | CFD | P00746 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.47 |
| ▸ | METTL14 | Q9HCE5 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601640 | 0.90 | PTPN11 (0.59) | PTPN11PTPN1PTPN6CFDRARA | |
| SCHEMBL15630531 | 0.89 | ADRB1 (0.55) | PTPN11PTPN1PTPN6RARARARB | |
| SCHEMBL4600863 | 0.88 | PTPN11 (0.56) | PTPN11PTPN1PTPN6CFDRARA | |
| SCHEMBL4601658 | 0.88 | PTPN11 (0.67) | PTPN11PTPN1PTPN6CFDS1PR3 | |
| SCHEMBL7959141 | 0.88 | PTPN11 (0.51) | PTPN11PTPN1PTPN6S1PR3ALDH1A1 | |
| SCHEMBL4602266 | 0.88 | PTPN11 (0.64) | PTPN11PTPN1PTPN6CFDRARA | |
| SCHEMBL4601436 | 0.87 | PTPN11 (0.59) | PTPN11PTPN1PTPN6CFDRARA | |
| SCHEMBL14610852 | 0.87 | PTPN11 (0.49) | PTPN11PTPN1PTPN6ALDH1A1MAPT | |
| SCHEMBL4603016 | 0.87 | PTPN11 (0.82) | PTPN11PTPN1PTPN6CFDRARA | |
| SCHEMBL4602854 | 0.86 | PTPN11 (0.57) | PTPN11PTPN1PTPN6CFDRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | claimed |
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | claimed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | claimed |
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | PTPN11 3529/4885PTPN1 3489/4885PTPN6 4028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.