Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | DHODH | Q02127 | 4/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4601688 | 0.84 | DHODH (0.50) | LMNADHODHPDE10ATSHRCYP2C9 | |
| SCHEMBL4601332 | 0.81 | DHODH (0.57) | LMNADHODHPDE10ATSHRTP53 | |
| Hydrochloric Acid SCHEMBL4602422 | 0.81 | DHODH (0.56) | LMNADHODHPDE10ATSHRTP53 | |
| SCHEMBL5005010 | 0.72 | TACR3 (0.55) | CYP2C9TACR3CYP2D6CYP2C19TACR2 | |
| SCHEMBL14610182 | 0.72 | TACR3 (0.58) | CYP2C9TACR3CYP2D6CYP2C19TACR2 | |
| SCHEMBL4601922 | 0.71 | DHODH (0.56) | LMNADHODHPDE10ATSHRTP53 | |
| SCHEMBL4603265 | 0.71 | TACR3 (0.57) | TSHRCYP2C9TACR3CYP2D6KDM4E | |
| SCHEMBL14009520 | 0.70 | TACR3 (0.77) | TSHRCYP2C9TP53TACR3CYP2D6 | |
| SCHEMBL5001458 | 0.70 | TACR3 (0.77) | TSHRCYP2C9TP53TACR3CYP2D6 | |
| SCHEMBL27725840 | 0.70 | TACR3 (0.53) | CYP2C9TACR3CYP2D6CYP2C19TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287492-A1 | Alkylpyridyl Quinolines as Nk3 Receptor Modulators | ASTRAZENECA AB (SE) | 2008-11-20 | — | — | US | disclosed |
| EP-1915361-A1 | ALKYLPYRIDYL QUINOLINES AS NK3 RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007018466-A1 | ALKYLPYRIDYL QUINOLINES AS NK3 RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287492-A1 | Alkylpyridyl Quinolines as Nk3 Receptor Modulators | ADORA3, KCNA3, TACR1 | LMNA 3173/4885DHODH 3718/4885PDE10A 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.