Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.59 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.59 |
| ▸ | ITGAL | P20701 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TACR3 | P29371 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155965 | 1.00 | MAPT (0.59) | MAPTHPGDKDM4ESMN1; SMN2ITGB2 | |
| SCHEMBL5149314 | 0.93 | ITGB2 (0.63) | MAPTHPGDKDM4ESMN1; SMN2ITGB2 | |
| SCHEMBL5149298 | 0.93 | ITGB2 (0.63) | MAPTHPGDKDM4ESMN1; SMN2ITGB2 | |
| SCHEMBL4601464 | 0.89 | MAPT (0.54) | MAPTHPGDKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL4601818 | 0.89 | MAPT (0.54) | MAPTHPGDKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL14557835 | 0.88 | MAPT (0.53) | MAPTHPGDKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL4601433 | 0.82 | MAPT (0.51) | MAPTHPGDKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5152256 | 0.82 | ITGB2 (0.50) | MAPTHPGDKDM4ESMN1; SMN2ITGB2 | |
| SCHEMBL14557577 | 0.82 | MAPT (0.47) | MAPTHPGDKDM4ESMN1; SMN2ITGB2 | |
| SCHEMBL4601437 | 0.82 | MAPT (0.51) | MAPTHPGDKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | MAPT 4047/4885HPGD 2557/4885KDM4E 2399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.