Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 8/20 | 0.63 |
| ▸ | ICAM1 | P05362 | 8/20 | 0.63 |
| ▸ | ITGAL | P20701 | 8/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149314 | 1.00 | ITGB2 (0.63) | ITGB2ICAM1ITGALMAPTHPGD | |
| SCHEMBL4601887 | 0.93 | MAPT (0.59) | ITGB2ICAM1ITGALMAPTHPGD | |
| SCHEMBL5155965 | 0.93 | MAPT (0.59) | ITGB2ICAM1ITGALMAPTHPGD | |
| SCHEMBL5152256 | 0.90 | ITGB2 (0.50) | ITGB2ICAM1ITGALMAPTHPGD | |
| SCHEMBL14007441 | 0.89 | ITGB2 (0.49) | ITGB2ICAM1ITGALMAPTHPGD | |
| SCHEMBL14557840 | 0.89 | ITGB2 (0.49) | ITGB2ICAM1ITGALMAPTHPGD | |
| SCHEMBL14007419 | 0.89 | ITGB2 (0.49) | ITGB2ICAM1ITGALMAPTHPGD | |
| SCHEMBL14557571 | 0.84 | ITGB2 (0.50) | ITGB2ICAM1ITGALMAPTHPGD | |
| SCHEMBL5155674 | 0.84 | MAPT (0.51) | ITGB2ICAM1ITGALMAPTHPGD | |
| SCHEMBL5155672 | 0.84 | MAPT (0.51) | ITGB2ICAM1ITGALMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | ITGB2 4080/4885ICAM1 4413/4885ITGAL 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.