Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207531 | 0.90 | PPARG (0.56) | PPARG | |
| SCHEMBL3217520 | 0.88 | PPARG (0.73) | PPARGSMN1; SMN2 | |
| SCHEMBL3207856 | 0.88 | PPARG (0.57) | PPARG | |
| SCHEMBL3205204 | 0.86 | PPARG (0.72) | PPARGSMN1; SMN2FFAR1 | |
| SCHEMBL3206453 | 0.86 | PPARG (0.71) | PPARGSMN1; SMN2 | |
| SCHEMBL3207082 | 0.84 | PPARG (0.72) | PPARGSMN1; SMN2 | |
| SCHEMBL3214072 | 0.82 | PPARG (0.57) | PPARGSMN1; SMN2FFAR1 | |
| SCHEMBL3214082 | 0.82 | PPARG (0.57) | PPARGSMN1; SMN2FFAR1 | |
| SCHEMBL3206768 | 0.82 | PPARG (0.72) | PPARGSMN1; SMN2FFAR1 | |
| SCHEMBL4601009 | 0.80 | SMN1; SMN2 (0.54) | PPARGSMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |