Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 11/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3204740 | 0.88 | PPARG (0.53) | SMN1; SMN2PPARGRAB9ALMNA | |
| SCHEMBL3205204 | 0.86 | PPARG (0.72) | SMN1; SMN2PPARGFFAR1LMNA | |
| SCHEMBL3212927 | 0.86 | RAB9A (0.56) | SMN1; SMN2PPARGRAB9ALMNACYP1A2 | |
| SCHEMBL3217520 | 0.84 | PPARG (0.73) | SMN1; SMN2PPARGLMNA | |
| SCHEMBL3206453 | 0.83 | PPARG (0.71) | SMN1; SMN2PPARGLMNAHPGD | |
| SCHEMBL3213488 | 0.83 | RAB9A (0.58) | SMN1; SMN2PPARGRAB9AFFAR1LMNA | |
| SCHEMBL3206768 | 0.81 | PPARG (0.72) | SMN1; SMN2PPARGFFAR1LMNALIPE | |
| SCHEMBL5106920 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2PPARGRAB9AFFAR1LMNA | |
| SCHEMBL4601900 | 0.80 | PPARG (0.60) | SMN1; SMN2PPARGFFAR1 | |
| SCHEMBL3207082 | 0.79 | PPARG (0.72) | SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |