Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 5/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.49 |
| ▸ | ITGAL | P20701 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14564875 | 0.94 | ITGB2 (0.49) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL14557654 | 0.94 | ITGB2 (0.49) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL14557744 | 0.94 | ITGB2 (0.47) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL4603045 | 0.92 | ITGB2 (0.40) | ITGB2ICAM1ITGALPPARGCCKBR | |
| SCHEMBL14564912 | 0.91 | HDAC3 (0.46) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL4600803 | 0.91 | HDAC3 (0.46) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL14557666 | 0.90 | ITGB2 (0.43) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL14159167 | 0.90 | MAPT (0.47) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL14557640 | 0.88 | ITGB2 (0.43) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL14564810 | 0.88 | ITGB2 (0.43) | ITGB2ICAM1ITGALMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | claimed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | claimed |