SCHEMBL4602121

SCHEMBL4602121

CCCC(F)(F)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15264084 0.80
SCHEMBL8610026 0.79
SCHEMBL347172 0.76
SCHEMBL28010820 0.76 CES2 (0.46)
SCHEMBL28295172 0.76 CES2 (0.46)
SCHEMBL18482581 0.74
SCHEMBL27811066 0.73
SCHEMBL7869314 0.71
SCHEMBL12236882 0.69 FDPS (0.30)
SCHEMBL5528902 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018054721-A1 PYRIDINE COMPOUNDS FOR CONTROLLING PHYTOPATHOGENIC HARMFUL FUNGI BASF SE (DE) 2018-03-29 WO disclosed
US-9187446-B2 Antibacterial agents: sidechainfluorinated myxopyronin derivatives RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-11-17 US disclosed
US-20150051275-A1 ANTIBACTERIAL AGENTS: SIDECHAINFLUORINATED MYXOPYRONIN DERIVATIVES HOWARD HUGHES MEDICAL INSTITUTE 2015-02-19 US disclosed
WO-2013142812-A1 ANTIBACTERIAL AGENTS: SIDECHAIN-FLUORINATED MYXOPYRONIN DERIVATIVES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2013-09-26 WO disclosed
US-20080170993-A1 THYMIDINE ANALOGS FOR IMAGING BAYER SCHERING PHARMA AG (DE) 2008-07-17 US disclosed
WO-2008049644-A1 THYMIDINE ANALOGS FOR IMAGING BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-05-02 WO disclosed
EP-1916003-A1 Thymidine analogs for imaging Bayer Schering Pharma Aktiengesellschaft (DE) 2008-04-30 EP disclosed