SCHEMBL4602272

SCHEMBL4602272

COc1ccccc1COCCCOc1ccc([C@H]2CCN(OC(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3ccc(OCOCC[Si](C)(C)C)cc3c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080260 1.00 REN (0.53) REN
SCHEMBL7080773 0.93 REN (0.51) REN
SCHEMBL7082625 0.91 REN (0.50) REN
SCHEMBL4603165 0.91 REN (0.53) REN
SCHEMBL6043932 0.91 REN (0.53) REN
SCHEMBL7079759 0.90 REN (0.49) REN
SCHEMBL7085119 0.90 REN (0.58) REN
SCHEMBL7083031 0.90 REN (0.47) REN
SCHEMBL7081003 0.89 REN (0.53) REN
SCHEMBL4603573 0.89 REN (0.53) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0979819-B1 Process for the production of substituted 3-hydroxypiperidines SPEEDEL PHARMA AG (CH) 2008-04-23 EP claimed