Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL28105553 | 1.00 | ALDH1A1 (0.73) | ALDH1A1TTRTSHR | |
| Tetrahydrofuran SCHEMBL27299023 | 0.96 | ALDH1A1 (0.67) | ALDH1A1TTRTSHR | |
| SCHEMBL14180051 | 0.92 | — | — | |
| Dioxane SCHEMBL27889984 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TTRTSHR | |
| Tetrahydrofuran SCHEMBL31402260 | 0.91 | — | — | |
| SCHEMBL8862667 | 0.89 | ALDH1A1 (0.57) | ALDH1A1TTRTSHR | |
| SCHEMBL14179993 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TTRTSHR | |
| SCHEMBL14180020 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TTRTSHR | |
| SCHEMBL14180006 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TTRTSHR | |
| SCHEMBL14180022 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TTRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110615753-A | Synthesis method of (3R,4S) -1-substituted-4-ethylpyrrole-3-carboxylic acid | 南京新酶合医药科技有限公司 | 2019-12-27 | — | — | CN | claimed |
| US-11655430-B2 | Coating composition for producing article | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) | 2023-05-23 | — | — | US | disclosed |
| US-20220154095-A1 | COATING COMPOSITION FOR PRODUCING ARTICLE | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) | 2022-05-19 | — | — | US | disclosed |
| US-11225628-B2 | Coating composition for producing article having slippery surface | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) | 2022-01-18 | — | — | US | disclosed |
| EP-3390404-B1 | TRICYCLIC COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2021-07-21 | — | — | EP | disclosed |
| EP-3081560-B1 | TAXANES COMPOUNDS, PREPARATION METHOD THEREFOR, AND USES THEREOF | JIANGSU TASLY DIYI PHARMACEUTICAL CO LTD (CN) | 2021-03-24 | — | — | EP | disclosed |
| US-20200239806-A1 | COATING COMPOSITION FOR PRODUCING ARTICLE HAVING SLIPPERY SURFACE | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) | 2020-07-30 | — | — | US | disclosed |
| EP-3405460-B1 | PROCESS FOR THE EPOXIDATION OF AN OLEFIN | EVONIK OPERATIONS GMBH (DE) | 2020-06-24 | — | — | EP | disclosed |
| CN-110615753-A | Synthesis method of (3R,4S) -1-substituted-4-ethylpyrrole-3-carboxylic acid | 南京新酶合医药科技有限公司 | 2019-12-27 | — | — | CN | disclosed |
| US-10377770-B2 | Tricyclic compounds and compositions as kinase inhibitors | NOVARTIS AG (CH) | 2019-08-13 | — | — | US | disclosed |
| US-4414392-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY, LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| US-4406688-A | Herbicidal 4-benzoyl-5-phenacyloxy-pyrazole derivatives, composition and method | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1983-09-27 | — | — | US | disclosed |
| EP-0080053-A1 | 3,5-Diphenyl-1H-1,2,4-triazoles with contragestational activity, pharmaceutical compositions thereof and process for their preparation | GRUPPO LEPETIT S.P.A. (IT) | 1983-06-01 | — | — | EP | disclosed |
| US-4301293-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY LTD. (JP) | 1981-11-17 | — | — | US | disclosed |
| EP-0029557-A2 | 7-Acylamino-3-substituted cephalosporanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-03 | — | — | EP | disclosed |
| US-4261729-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY LIMITED (JP) | 1981-04-14 | — | — | US | disclosed |
| US-4205180-A | CHEMICAL INTERMEDIATES FOR NOVEL CEPHALOSPORIN COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-05-27 | — | — | US | disclosed |
| EP-0008759-A2 | New process for preparing an 1H-indazol-3-ylacetic acid derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-03-19 | — | — | EP | disclosed |
| US-4146726-A | HERBICIDES | SANKYO COMPANY LIMITED (JP) | 1979-03-27 | — | — | US | disclosed |
| US-4063925-A | Herbicidal compositions | SANKYO COMPANY LIMITED (JA) | 1977-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377770-B2 | Tricyclic compounds and compositions as kinase inhibitors | BRAF, RAF1, MAP3K1 | ALDH1A1 1892/4885TTR 4476/4885TSHR 3987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.