Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604870 | 0.87 | AR (0.41) | ARPGRCYP11B1CYP11B2 | |
| SCHEMBL13779690 | 0.80 | AR (0.43) | ARPGRCYP11B1CYP11B2 | |
| SCHEMBL4603841 | 0.80 | AR (0.45) | ARPGR | |
| SCHEMBL4194003 | 0.79 | AR (0.42) | ARPGRCYP11B1CYP11B2 | |
| SCHEMBL4199472 | 0.78 | AR (0.41) | ARPGR | |
| SCHEMBL14619067 | 0.78 | AR (0.41) | ARPGRCYP11B1CYP11B2 | |
| SCHEMBL4604132 | 0.77 | AR (0.44) | ARPGR | |
| SCHEMBL4601201 | 0.74 | AR (0.46) | ARPGR | |
| SCHEMBL4196449 | 0.73 | AR (0.59) | ARPGR | |
| SCHEMBL4199094 | 0.71 | AR (0.57) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915338-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007017754-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2007-02-15 | — | — | WO | disclosed |