Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199472 | 0.89 | AR (0.41) | ARPGR | |
| SCHEMBL4194003 | 0.89 | AR (0.42) | ARCYP11B1CYP11B2PGR | |
| SCHEMBL14619067 | 0.88 | AR (0.41) | ARCYP11B1CYP11B2PGR | |
| SCHEMBL4198718 | 0.84 | AR (0.52) | ARCYP11B1CYP11B2PGR | |
| SCHEMBL4604870 | 0.80 | AR (0.41) | ARCYP11B1CYP11B2PGR | |
| SCHEMBL14619455 | 0.80 | AR (0.38) | AR | |
| SCHEMBL4602336 | 0.80 | AR (0.44) | ARCYP11B1CYP11B2PGR | |
| SCHEMBL14619457 | 0.79 | AR (0.39) | AR | |
| SCHEMBL4191250 | 0.78 | AR (0.48) | ARCYP11B1CYP11B2PGR | |
| SCHEMBL13780042 | 0.76 | CYP11B1 (0.34) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170886-A1 | ANDROGEN MODULATORS | PFIZER INC | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170886-A1 | ANDROGEN MODULATORS | AR, NR5A1, SHBG | AR 1/4885CYP11B1 47/4885CYP11B2 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.