SCHEMBL460253

SCHEMBL460253

C=C=CCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.52
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ARG2 P78540 1/20 0.40
CALM1 P0DP23 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
IDO1 P14902 4/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
TRPA1 O75762 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28630232 0.81 MAOB (0.48) MAOBCA1CA2ARG2CALM1
SCHEMBL29094387 0.80 MAOB (0.52) MAOBCA1CA2ARG2CALM1
SCHEMBL861788 0.77 MAOB (0.55) MAOBCA1CA2ARG2CALM1
SCHEMBL14144482 0.76 ALDH1A1 (0.44) MAOBNOS1TSHRLOXL2ALDH1A1
SCHEMBL6657714 0.76 IDO1 (0.41) SMN1; SMN2IDO1TSHRTP53ALDH1A1
SCHEMBL3035505 0.76 MAOB (0.42) MAOBSMN1; SMN2LOXL2ALDH1A1
SCHEMBL811590 0.76 CYP3A4 (0.37) IDO1
SCHEMBL3042520 0.75 MAOB (0.52) MAOBCA1CA2ARG2CALM1
SCHEMBL15282878 0.75 MAOB (0.52) MAOBCA1CA2ARG2CALM1
SCHEMBL57808 0.75 MAOB (0.52) MAOBCA1CA2ARG2CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118772026-A Method for synthesizing (E) -1-phenyl-3- (p-toluenesulfonyl) but-2-en-1-one 衡阳师范学院 2024-10-15 CN claimed
CN-116135848-A Coumarin compound and preparation method and application thereof 中国科学院兰州化学物理研究所 2023-05-19 CN claimed
CN-109679550-A Hot-melt pressure-sensitive adhesive for edge folding of soft package lithium battery and preparation method thereof 烟台德邦科技有限公司 2019-04-26 CN claimed
CN-108024591-B Footwear buffer compositions and footwear buffer component 株式会社泰已科 2019-03-15 CN claimed
CN-108024591-A Footwear are with buffer compositions and footwear buffer component 株式会社泰已科 2018-05-11 CN claimed
CN-103568394-B Moisture barrier films and electric/electronic 日东电工株式会社 2017-06-16 CN claimed
CN-103568394-A Moisture-proof film and electrical/electronic device NITTO DENKO CORP 2014-02-12 CN claimed
CN-103571361-A Adhesive sheet and electrical/electronic equipment NITTO DENKO CORP 2014-02-12 CN claimed
US-8147958-B2 Poly(arylene ether) composition and articles SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-04-03 US claimed
US-7772322-B2 coated wire; electronics; flexibility, durability; block polymer; controlled distribution copolymer block having terminal regions that are rich in alkylene units; flame retardant; halogen and PVC free; endcapped polyphenylene ether; olefin-styrene block polymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-08-10 US claimed
CN-101160611-A Shrink labels GUNZE KK (JP) 2008-04-09 CN claimed
EP-0866068-B1 PROCESS FOR THE PREPARATION OF BENZYL-METAL COMPOUNDS AND PROCESS FOR THE PREPARATION OF 4-PHENYL-1-BUTENES BY THE USE OF THE SAME KI CHEMICAL INDUSTRY CO LTD (JP) 2002-07-31 EP claimed
EP-0101023-A1 Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process BANYU PHARMACEUTICAL CO., LTD. (JP) 1984-02-22 EP claimed
CN-122060324-A Resin composition, prepreg and metal foil laminated plate thereof 科钛芯材(江苏)科技有限公司 2026-05-19 CN disclosed
CN-122059862-A Efficient preparation method of thioester and cyclic thioester compounds 广州医科大学 2026-05-19 CN disclosed
CN-119570356-A Wear-resistant butterfly valve and processing method thereof 迪力阀门科技有限公司 2025-03-07 CN disclosed
WO-2006065497-A1 FLAME RETARDANT ELECTRICAL WIRE GENERAL ELECTRIC COMPANY (US) 2006-06-22 WO disclosed
WO-2006065519-A1 ELECTRICAL WIRE AND METHOD OF MAKING AN ELECTRICAL WIRE GENERAL ELECTRIC COMPANY (US) 2006-06-22 WO disclosed
US-20030220507-A1 Enantioselective transformation of alpha,beta-unsaturated ketones using chiral organic catalysts CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-11-27 US disclosed
US-4339397-A Method for the preparation of a sodium salt of 1-alkyne compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1982-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220507-A1 Enantioselective transformation of alpha,beta-unsaturated ketones using chiral organic catalysts HACL2, EBP, MED1 MAOB 2258/4885CA1 988/4885CA2 925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.