Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 19/20 | 0.58 |
| ▸ | CA2 | P00918 | 19/20 | 0.58 |
| ▸ | CA12 | O43570 | 11/20 | 0.58 |
| ▸ | CA9 | Q16790 | 11/20 | 0.58 |
| ▸ | CA5A | P35218 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604104 | 0.90 | CA2 (0.59) | CA1CA2CA12CA9CA5A | |
| SCHEMBL4603625 | 0.89 | CA1 (0.58) | CA1CA2CA12CA9CA5A | |
| SCHEMBL4604312 | 0.87 | CA1 (0.54) | CA1CA2CA12CA9CA5A | |
| SCHEMBL4604199 | 0.87 | CA2 (0.58) | CA1CA2CA12CA9CA5A | |
| SCHEMBL4603727 | 0.86 | CA1 (0.49) | CA1CA2CA12CA9CA5A | |
| SCHEMBL4604203 | 0.85 | CA1 (0.56) | CA1CA2CA12CA9CA5A | |
| SCHEMBL4603542 | 0.85 | MEN1 (0.53) | MEN1KMT2A | |
| SCHEMBL2638748 | 0.83 | CA1 (0.59) | CA1CA2CA12CA9CA5A | |
| SCHEMBL4604671 | 0.83 | CA1 (0.53) | CA1CA2CA12CA9CA5A | |
| SCHEMBL4603722 | 0.82 | CA1 (0.49) | CA1CA2CA12CA9CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940781-A1 | PHENYL-ACETAMIDE NNRT INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-07-09 | — | — | EP | claimed |
| WO-2007045573-A1 | PHENYL-ACETAMIDE NNRT INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-04-26 | — | — | WO | claimed |