Cyclamic Acid

Cyclamic Acid

SCHEMBL4602644

O=C(O)C(=O)O.O=S(=O)(O)NC1CCCCC1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Cyclamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.54
CA12 O43570 2/20 0.54
CA7 P43166 2/20 0.54
CA14 Q9ULX7 2/20 0.54
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.48
EPHX1 P07099 6/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
KDM4E B2RXH2 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.43
CYP3A4 P08684 1/20 0.43
EPHX2 P34913 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
RECQL P46063 1/20 0.41
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclamic Acid SCHEMBL6227 0.91 CA12 (0.64) CA1CA12CA7CA14CA2
Cyclamic Acid SCHEMBL18585752 0.91 CA12 (0.64) CA1CA12CA7CA14CA2
SCHEMBL1727205 0.91 CA12 (0.64) CA1CA12CA7CA14CA2
Cyclamic Acid SCHEMBL11686696 0.91 CA12 (0.64) CA1CA12CA7CA14CA2
SCHEMBL1726879 0.91 CA12 (0.64) CA1CA12CA7CA14CA2
SCHEMBL1727915 0.91 CA12 (0.64) CA1CA12CA7CA14CA2
SCHEMBL1726858 0.91 CA12 (0.64) CA1CA12CA7CA14CA2
Cyclamic Acid SCHEMBL3790764 0.89 CA1 (0.52) CA1CA12CA7CA14CA2
Cyclamic Acid SCHEMBL120573 0.89 CA12 (0.61) CA1CA12CA7CA14CA2
Cyclamic Acid SCHEMBL3723387 0.89 CA12 (0.61) CA1CA12CA7CA14CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1912505-A2 MICROEMULSIONS AND CONCENTRATES COMPRISING FIPRONIL Bayer CropScience S.A. (FR) 2008-04-23 EP disclosed
EP-1761490-A1 3'-ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACIDS Bayer CropScience Aktiengesellschaft (DE) 2007-03-14 EP disclosed
WO-2007017040-A2 MICROEMULSIONS AND CONCENTRATES COMPRISING FIPRONIL BAYER CROPSCIENCE S.A. (FR) 2007-02-15 WO disclosed
EP-1732930-A2 2,4,6-PHENYLSUBSTITUTED CYCLIC KETOENOLES Bayer CropScience Aktiengesellschaft (DE) 2006-12-20 EP disclosed
EP-1725104-A2 OIL-BASED SUSPENSION CONCENTRATES Bayer CropScience Aktiengesellschaft (DE) 2006-11-29 EP disclosed
EP-1656382-A2 4-BIPHENYLSUBSTITUTED PYRAZOLIDIN-3,5-DIONE DERIVATIVES Bayer CropScience Aktiengesellschaft (DE) 2006-05-17 EP disclosed
EP-1656383-A1 4-BIPHENYL-SUBSTITUTED 4-SUBSTITUTED PYRAZOLIDIN-3,5-DIONES PESTICIDE AGENT AND/OR MICROBICIDE AND/OR HERBICIDE Bayer CropScience AG (DE) 2006-05-17 EP disclosed
EP-1648898-A1 HETARYL-SUBSTITUTED PYRAZOLIDINDIONE DERIVATIVES WITH PESTICIDAL CHARACTERISTICS Bayer CropScience AG (DE) 2006-04-26 EP disclosed
WO-2006000355-A1 3'-ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACIDS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2006-01-05 WO disclosed
WO-2005092897-A2 2,4,6-PHENYLSUBSTITUTED CYCLIC KETOENOLES BAYER CROPSCIENCE AG (DE) 2005-10-06 WO disclosed
WO-2005084435-A2 OIL-BASED SUSPENSION CONCENTRATES BAYER CROPSCIENCE AG (DE) 2005-09-15 WO disclosed
EP-1572663-A1 BIPHENYLCARBOXAMIDES Bayer CropScience AG (DE) 2005-09-14 EP disclosed
WO-2005016933-A1 4-BIPHENYL-SUBSTITUTED 4-SUBSTITUTED PYRAZOLIDIN-3,5-DIONES PESTICIDE AGENT AND/OR MICROBICIDE AND/OR HERBICIDE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-02-24 WO disclosed
WO-2005016873-A2 4-BIPHENYLSUBSTITUTED PYRAZOLIDIN-3,5-DIONE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-02-24 WO disclosed
WO-2005005428-A1 HETARYL-SUBSTITUTED PYRAZOLIDINDIONE DERIVATIVES WITH PESTICIDAL CHARACTERISTICS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-01-20 WO disclosed
WO-2004054982-A1 BIPHENYLCARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2004-07-01 WO disclosed