⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27207208 | 1.00 | — | — | |
| SCHEMBL470470 | 1.00 | — | — | |
| SCHEMBL6118224 | 1.00 | — | — | |
| SCHEMBL6118249 | 0.86 | LMNA (0.42) | — | |
| SCHEMBL12685324 | 0.86 | LMNA (0.42) | — | |
| SCHEMBL25378867 | 0.80 | — | — | |
| SCHEMBL3589237 | 0.73 | — | — | |
| SCHEMBL3601341 | 0.73 | — | — | |
| SCHEMBL408223 | 0.72 | — | — | |
| SCHEMBL284532 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132513-A1 | BENZAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT | AGENEBIO, INC. | 2024-04-25 | — | — | US | disclosed |
| CN-109311864-B | Heteroaryl substituted pyridines and methods of use | 艾伯维公司 | 2022-05-10 | — | — | CN | disclosed |
| EP-3464282-B1 | HETEROARYL SUBSTITUTED PYRIDINES AND METHODS OF USE | ABBVIE OVERSEAS SARL (LU) | 2020-04-22 | — | — | EP | disclosed |
| US-10604515-B2 | Heteroaryl substituted pyridines and methods of use | ABBVIE S.Á.R.L. (LU) | 2020-03-31 | — | — | US | disclosed |
| EP-3464282-A1 | HETEROARYL SUBSTITUTED PYRIDINES AND METHODS OF USE | AbbVie S.À.R.L. (LU) | 2019-04-10 | — | — | EP | disclosed |
| US-20190055229-A1 | Heteroaryl Substituted Pyridines and Methods of Use | ABBVIE S.Á.R.L. (LU) | 2019-02-21 | — | — | US | disclosed |
| US-10138227-B2 | Heteroaryl substituted pyridines and methods of use | ABBVIE S.Á.R.L. (LU) | 2018-11-27 | — | — | US | disclosed |
| WO-2017208115-A1 | HETEROARYL SUBSTITUTED PYRIDINES AND METHODS OF USE | AbbVie S.à.r.l. (LU) | 2017-12-07 | — | — | WO | disclosed |
| US-20170349576-A1 | HETEROARYL SUBSTITUTED PYRIDINES AND METHODS OF USE | ABBVIE S.Á.R.L. (LU) | 2017-12-07 | — | — | US | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |