Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193458 | 0.85 | AR (0.61) | ARPGR | |
| SCHEMBL4603692 | 0.82 | AR (0.55) | AR | |
| SCHEMBL4201441 | 0.81 | AR (0.49) | ARPGR | |
| SCHEMBL4601213 | 0.80 | AR (0.55) | AR | |
| SCHEMBL2473339 | 0.80 | NOTUM (0.57) | ARPGRRXRARXRBRXRG | |
| SCHEMBL14967039 | 0.79 | MAPT (0.62) | MAPT | |
| SCHEMBL13780061 | 0.78 | AR (0.46) | ARPGR | |
| SCHEMBL4193337 | 0.78 | AR (0.47) | ARPGR | |
| SCHEMBL3412694 | 0.78 | AR (0.48) | ARMAPTPGR | |
| SCHEMBL4191279 | 0.76 | AR (0.59) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915338-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007017754-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2007-02-15 | — | — | WO | disclosed |