SCHEMBL2473339

SCHEMBL2473339

COC(=O)c1ccc(C#N)c(C(F)(F)F)c1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.57
AR P10275 15/20 0.51
PGR P06401 3/20 0.51
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
TAS2R14 Q9NYV8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29653930 0.88 NOTUM (0.61) NOTUMARPGR
SCHEMBL17110468 0.88 NOTUM (0.61) NOTUMARPGR
SCHEMBL17672487 0.85 NOTUM (0.57) NOTUM
SCHEMBL4952291 0.83 PDK2 (0.49) NOTUMARPGR
SCHEMBL4193337 0.81 AR (0.47) ARPGR
SCHEMBL17672598 0.81 NOTUM (0.54) NOTUMAR
SCHEMBL17843509 0.81 RXRA (0.55) ARPGRRXRARXRBRXRG
SCHEMBL8148281 0.80 CA1 (0.52)
SCHEMBL1997248 0.80 NOTUM (0.73) NOTUM
SCHEMBL17672783 0.80 NOTUM (0.52) NOTUMAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590107-B2 Cerium (IV) complexes and their use in organic electronics Credoxys GmbH (DE) 2026-03-31 US disclosed
EP-4557929-A2 CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS CREDOXYS GmbH (DE) 2025-05-21 EP disclosed
EP-4029069-B1 CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS Credoxys GmbH (DE) 2025-04-09 EP disclosed
US-20230092935-A1 CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS Credoxys GmbH (DE) 2023-03-23 US disclosed
EP-4029069-A1 CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS Credoxys GmbH c/o Institut for Applied Physics (DE) 2022-07-20 EP disclosed
CN-114364653-A Cerium (IV) complexes and their use in organic electronic components 克雷多西斯有限公司 2022-04-15 CN disclosed
WO-2021048044-A1 CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS Technische Universität Dresden (DE) 2021-03-18 WO disclosed
US-20110311485-A1 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE ALMIRALL S.A. (ES) 2011-12-22 US disclosed
US-20110311485-A1 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE ALMIRALL S.A. (ES) 2011-12-22 US disclosed
EP-2370431-A1 1, 2, 4 -OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE Almirall S.A. (ES) 2011-10-05 EP disclosed
WO-2010072352-A1 1, 2, 4 -OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE ALMIRALL S.A. (ES) 2010-07-01 WO disclosed
WO-2010072352-A1 1, 2, 4 -OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE ALMIRALL S.A. (ES) 2010-07-01 WO disclosed
EP-2202232-A1 1,2,4-oxadiazole derivatives and their therapeutic use Laboratorios Almirall, S.A. (ES) 2010-06-30 EP disclosed
EP-2202232-A1 1,2,4-oxadiazole derivatives and their therapeutic use Laboratorios Almirall, S.A. (ES) 2010-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110311485-A1 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE S1PR1, S1PR2, S1PR3 NOTUM 4067/4885AR 934/4885PGR 925/4885
US-12590107-B2 Cerium (IV) complexes and their use in organic electronics CLIC4, CCR4, LOXL4 NOTUM 1702/4885AR 3434/4885PGR 1671/4885
US-20230092935-A1 CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS CLIC4, KCNN4, CLN6 NOTUM 264/4885AR 4437/4885PGR 2124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.